Low-intensity pulsed ultrasound (LIPUS) is a technology that can be used for therapeutic purposes. It exploits low intensity and pulsed mechanical waves in order to induce regenerative and anti-inflammatory effects on biological tissues, such as bone, [1] cartilage, and tendon. [2] .

lipus又叫低能量脉冲式超声波，属于微能量医学的一种，类似红外线微波、射频等，从被提出治疗ED存疑到目前为止，已经有十年，彻底投入临床治疗可以说从去年开始。

Low Intensity Pulsed Ultrasound Therapy (LIPUS) is a non-invasive treatment and aims to reduce fracture healing time and avoid non-union by delivering micro-mechanical stress to the bone to stimulate bone healing.

2021年6月1日 · LIPUS was approved in the US for the treatment of established non-unions in 2000, and is also approved around the world. In this article, we present relevant literature on the effect of LIPUS on bone healing in patients with acute fractures and non-unions and provide a molecular explanation for the effects of LIPUS on bone healing.

Low-intensity pulsed ultrasound (LIPUS), a form of mechanical stimulation, has become a popular non-invasive therapeutic modality in the fields of traumatology and regenerative medicine (Mei and Zhang, 2021). In past decades, the application of ultrasound in medicine, especially for diagnostics, surgery, and therapy, has been wildly investigated.

2025年3月27日 · LIPUS also enhances extracellular matrix deposition and mineralization. Osteoblasts exposed to LIPUS produce more type I collagen and alkaline phosphatase, critical for bone matrix development. Additionally, LIPUS upregulates bone morphogenetic proteins (BMPs), particularly BMP-2 and BMP-7, which initiate and sustain osteogenesis.

相较于高强度聚焦超声(high intensity focused ultrasound，HIFU)，LIPUS具有对组织无损伤、分辨率高的优点，主要依靠非热效应发挥功效。LIPUS的主要参数从不同的角度影响超声结构，进而影响其作用效果。

低强度脉冲超声（lipus）是临床常见的物理治疗手段之一，可用于促进骨折愈合以及治疗陈旧性骨不连。局部血管、神经和骨组织密切相关、互相影响，是骨组织再生的重要影响因素。

2023年4月8日 · 低能量脉冲式超声波治疗仪(Low-intensitypulsedultrasound,LIPUS)，称“男性健康太空舱”。 2023年我院男科诊疗研究室首家引进了国际先进设备、我国自主研发、国家双创新级设备--LIPUS低强度脉冲式超声波ED治疗仪。

2017年2月21日 · Does low intensity pulsed ultrasound (LIPUS) accelerate recovery in adults and children who have experienced bone fractures or osteotomy (cutting of a bone)? An expert panel rapidly produced these recommendations based on a linked systematic review triggered by a large multicentre randomised trial in adults with tibial fracture.