LIN28 - Wikipedia
Lin-28 homolog A is a protein that in humans is encoded by the LIN28 gene. [5] [6] LIN28 encodes an RNA-binding protein [7] that binds to and enhances the translation of the IGF-2 …
Lin28信号通路与肿瘤 - cjco.cn
Lin28是一种结构上高度保守的RNA结合蛋白，其在机体正常生长发育代谢及某些疾病状态，如肿瘤发生发展中有重要作用。 近年的研究发现，Lin28在机体中的过表达能够抑制let-7 miRNA的 …
LIN28: roles and regulation in development and beyond
2015年7月15日 · LIN28 is an RNA-binding protein that is best known for its roles in promoting pluripotency via regulation of the microRNA let-7. However, recent studies have uncovered …
张进课题组Protein & Cell 揭示核仁定位的RNA结合蛋白LIN28调控 …
2021年8月29日 · LIN28是一种RNA结合蛋白，在小鼠胚胎早期发育、干细胞分化/重编程、肿瘤发生和代谢中具有重要作用。 以往的研究主要集中于它在细胞质中与Let-7 microRNA前体 …
Lin28, a major translation reprogramming factor, gains access …
2021年3月19日 · The RNA-binding protein Lin28 (Lin28a) is an important pluripotency factor that reprograms translation and promotes cancer progression.
LIN28A Gene - GeneCards | LN28A Protein | LN28A Antibody
2025年3月30日 · LIN28A (Lin-28 Homolog A) is a Protein Coding gene. Diseases associated with LIN28A include Medulloepithelioma and Embryonal Tumor With Multilayered Rosettes, C19mc …
LIN28 Binds Messenger RNAs at GGAGA Motifs and Regulates …
2012年10月26日 · LIN28 is a conserved RNA-binding protein implicated in pluripotency, reprogramming, and oncogenesis. It was previously shown to act primarily by blocking let-7 …
Exploring Lin28 proteins: Unravelling structure and functions with ...
2023年12月15日 · Altered expression levels of LIN28A and LIN28B have been proposed as diagnostic and/or prognostic markers for various malignancies. This review discusses the …
Lin28: A MicroRNA Regulator with a Macro Role - Cell Press
2010年2月19日 · Lin28, a highly conserved RNA-binding protein, has emerged as a modulator of the processing of the let-7 microRNA. This role for Lin28 has important implications for our …
Mechanisms of Lin28-Mediated miRNA and mRNA Regulation—A …
Lin28 (cell lineage abnormal 28) is a conserved RNA-binding protein in higher eukaryotes that regulates several important cellular functions associated with development, glucose …