LILRB1 - Wikipedia
Leukocyte immunoglobulin-like receptor subfamily B member 1 is a protein that in humans is encoded by the LILRB1 gene. [3][4] This gene is a member of the leukocyte immunoglobulin …
抑制性白细胞免疫球蛋白样受体：LILRB - 知乎
BND-22 是靶向LILRB1受体的“first-in-class”人源化IgG4单克隆抗体，目标是用于治疗实体瘤，由Biond Biologics公司研发。 通过阻断HLA-G和LILRB1互作导致的免疫抑制，其可以激活T细胞 …
抗癌理想靶点新选择：LILRBs - 南模生物
LILRB1（也被称作ILT2）包含四个胞外Ig结构域，一个跨膜结构域和四个胞质ITIM基序。 在LILRB家族中，LILRB1的细胞分布最为广泛，包括原代NK细胞、B 细胞、各种T细胞群、单核 …
LILRB1 Gene - GeneCards | LIRB1 Protein | LIRB1 Antibody
2025年3月30日 · LILRB1 (Leukocyte Immunoglobulin Like Receptor B1) is a Protein Coding gene. Diseases associated with LILRB1 include Human Cytomegalovirus Infection and Malaria. …
抗癌新方向，免疫检查点LILRB - 知乎
LILRB1和LILRB2受体通过与 人白细胞抗原-G（HLA-G） 的相互作用抑制 细胞毒性T细胞 、NK细胞和B细胞，诱导T细胞无能，调节骨髓细胞，并促进Tregs细胞。
Leukocyte immunoglobulin-like receptor B1 (LILRB1) protects …
2024年7月9日 · Here, we show that the leukocyte immunoglobulin-like receptor B1 (LILRB1), a transmembrane receptor conducting negative immune response, is a top-ranked gene …
LILRB靶点研发：行而不辍，未来可期 - 知乎
BND-22是由以色列创新生物药公司Biond Biologics开发的一款靶向LILRB1受体的抗体拮抗剂，拟开发用于治疗实体瘤。 临床前研究表明，BND-22通过靶向巨噬细胞中LILRB1介导的“不吃我” …
LILRB1-directed CAR-T cells for the treatment of hematological ...
5 天之前 · These findings establish LILRB1 as a novel target for cancer immunotherapy and show evidence for the preclinical efficacy of LILRB1 CAR-T cells against haematological …
Perspectives of targeting LILRB1 in innate and adaptive immune ...
A novel emerging potential target for immune checkpoint therapy is leukocyte immunoglobulin-like receptor subfamily B member 1 (LILRB1). LILRB1 belongs to the superfamily of leukocyte …
LILRB1 leukocyte immunoglobulin like receptor B1 [ (human)]
2025年2月8日 · LILRB1 is used for immune evasion by Plasmodium falciparum by associating with RIFINs. Data indicate the MHC class I-LILRB1 signaling axis as an important regulator of …