Levothyroxine, also known as L-thyroxine or T4, is a synthetic form of the thyroid hormone thyroxine. Its chemical structure is similar to the endogenous hormone produced by the thyroid gland. Key components: Levothyroxine is composed of four iodine atoms attached to a tyrosine residue. The molecular formula of levothyroxine is C15H11I4NO4 ...

Explore the chemical structure of levothyroxine, a synthetic form of thyroid hormone used to treat hypothyroidism, and understand its molecular composition and pharmacological properties.

Levothyroxine is variably absorbed from the GI tract (range: 40-80%). In animals, levothyroxine is absorbed in the proximal and middle jejunum; the drug is not absorbed from the stomach or distal colon and little, if any, absorption occurs in the duodenum.

Levothyroxine, also known as L-thyroxine, is a synthetic form of the thyroid hormone thyroxine (T 4). [5] [8] It is used to treat thyroid hormone deficiency (hypothyroidism), including a severe form known as myxedema coma. [5] It may also be used to treat and prevent certain types of thyroid tumors. [5] It is not indicated for weight loss. [5]

ChemSpider record containing structure, synonyms, properties, vendors and database links for Levothyroxine, 51-48-9, Thyroxine, XUIIKFGFIJCVMT-LBPRGKRZSA-N

Levothyroxine Sodium is the sodium salt of levothyroxine, a synthetic levoisomer of thyroxine (T4) that is similar to the endogenous hormone produced by the thyroid gland. In peripheral tissues, levothyroxine is deiodinated by 5'-deiodinase to form triiodothyronine (T3).

As shown in the following diagram, the thyroid hormones are basically two tyrosines linked together with the critical addition of iodine at three or four positions on the aromatic rings. The number and position of the iodines is important.

1976年1月1日 · Structure-activity relationships are conveniently discussed in terms of single structural variations of T4 in the regions a-f (Fig. 2). Only structures containing appropriately substituted aromatic rings separated by a connecting atom, have shown thyroxine-like …

Levothyroxine is a synthetic T4 hormone used to treat hypothyroidism that can be used along with surgery and radioiodine therapy to manage thyrotropin-dependent well-differentiated thyroid cancer.

2021年10月14日 · Levothyroxine-d3 | C15H11I4NO4 | CID 168007130 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.