白三烯（Leukotriene，LT）是一群来自花生四烯酸或其他非饱和脂肪酸的类花生酸 炎症介质，含三个共轭双键的20碳直链羟基酸，与过敏性反应有关的生物活性物质，其他与过敏性反应有关的生物活性物质包括组胺、缓激肽、血小板活化因子等。

Leukotrienes are a family of eicosanoid inflammatory mediators produced in leukocytes by the oxidation of arachidonic acid (AA) and the essential fatty acid eicosapentaenoic acid (EPA) by the enzyme arachidonate 5-lipoxygenase. [1][2][3]

Leukotrienes are derived from arachidonic acid, the precursor of prostaglandins. There are two families of leukotrienes. The first group acts primarily in conditions in which inflammation is dependent on neutrophils, such as cystic fibrosis, inflammatory bowel disease, and psoriasis.

【英文名称】：leukotriene;LT 【说明】：从 花生四烯酸 在 白细胞 中代谢产物分离得到的具有共轭三烯结构的二十碳不饱和酸。 可按 取代基 性质分为A、B、C、D、E、F六类，其中LTA3的结构为2001下标3代表 碳链 中双键总数。

2023年8月14日 · Leukotrienes (LTs) are a group of inflammatory mediators that belong to the eicosanoid family. Their synthesis, primarily by leukocytes, is spurred by a variety of immunologic and nonimmunologic stimuli, including antigens, immune complexes, complement, cytokines, osmotic challenges, and pollutants, among others.

2021年6月2日 · Leukotriene modifiers, also called leukotriene receptor antagonists or leukotriene synthesis inhibitors, are medications that block the effect of leukotrienes or stop your body from producing them. These drugs are used to prevent or lessen the symptoms of:

白三烯B4（英語： Leukotriene B4 ）是一种与炎症反应有关的白三烯类物质。 它由响应炎症介质的 白细胞 产生，让白细胞活化并依附在 內皮 上，允许其穿过组织 [ 1 ] 。

2017年1月1日 · Leukotrienes, i.e., leukotrienes (LT) B 4, C 4, D 4, and E 4, are lipid mediators of inflammation, derived from the 5-lipoxygenase pathway of arachidonic acid metabolism (Samuelsson 1983; Fig. 1). The name originates from their leukocyte origin (leuko-) and their three conjugated double bonds (triene).

2023年12月7日 · Leukotrienes, derived from arachidonic acid metabolism, exhibit diverse structures, driving their distinct functions. Arachidonic acid serves as their common backbone. Leukotriene A4 (LTA4), a pivotal intermediate, undergoes enzymatic transformations to yield leukotriene B4 (LTB4) and cysteinyl leukotrienes (LTC4, LTD4, LTE4).

白三烯B4（英语：Leukotriene B4）是一种与 炎症 反应有关的 白三烯 类物质。 它由响应炎症介质的 白细胞 产生，让白细胞活化并依附在 内皮 上，允许其穿过组织。 在 中性粒细胞 中，它也是一种强效化学诱导物，并且能够诱导形成 活性氧类 和 溶酶体 中酶的释放。 它由白三烯A4水解酶水解白三烯A4而来。 白三烯B4（英语：Leukotriene B4）是一种与炎症反应有关的白三烯类物质。