LRP1 - Wikipedia
Low density lipoprotein receptor-related protein 1 (LRP1), also known as alpha-2-macroglobulin receptor (A2MR), apolipoprotein E receptor (APOER) or cluster of differentiation 91 (CD91), is …
LRP1 Gene - GeneCards | LRP1 Protein | LRP1 Antibody
2025年3月30日 · LRP1 (LDL Receptor Related Protein 1) is a Protein Coding gene. Diseases associated with LRP1 include Developmental Dysplasia Of The Hip 3 and Keratosis Pilaris …
Nature：神经退行性疾病治疗下一个新靶点——LRP1 - 知乎
4月1日，在Nature上发表的一篇论文中，Kosik教授和他的团队揭示了tau蛋白在神经元之间的一种扩散机制： 低密度脂蛋白受体相关蛋白1 (low-denisity lipoprotein receptor-related protein …
LRP1 Mediates Endocytosis Activity and Is a Potential Therapeutic ...
5 天之前 · 3 Structure and Function of LRP1. LRP1 is a versatile and multifunctional receptor essential for mediating endocytosis and cellular signaling [43, 44].It is initially synthesized as a …
LRP1 is a master regulator of tau uptake and spread - Nature
2020年4月1日 · Our results identify LRP1 as a key regulator of tau spread in the brain, and therefore a potential target for the treatment of diseases that involve tau spread and aggregation.
The molecular mechanism of LRP1 in physiological vascular …
2021年7月1日 · LRP1 protects the vasculature by limiting remodeling events through the modulation of the TGF-β signaling pathway. LRP1 also plays an important role in the …
Unraveling the Role of LRP1 in Alzheimer’s Disease: A ... - Springer
6 天之前 · LRP1, also known as the α2-macroglobulin receptor or CD91, is a widely expressed type I transmembrane protein (Fig. 1) (Bell and Zlokovic 2009).It wasfirst identified in 1988 by …
综述：解析低密度脂蛋白受体相关蛋白 1（LRP1）在阿尔茨海默病 …
4 天之前 · 由于 lrp1 在 aβ 清除和神经炎症调节方面的重要作用，增强 lrp1 的活性成为了 ad 治疗的一个重要方向。 通过运动、药物干预和合理饮食等方式提高 LRP1 的表达水平，可以有效 …
LRP1 LDL receptor related protein 1 [ Homo sapiens (human) ]
2025年2月9日 · Title: LRP1 induces anti-PD-1 resistance by modulating the DLL4-NOTCH2-CCL2 axis and redirecting M2-like macrophage polarisation in bladder cancer. LRP1 is the cell …
Cell Metab 四川大学华西医院李涛教授团队揭示LRP1介导ARF1 …
2024年9月19日 · 文章系统解析了低密度脂蛋白相关受体蛋白1 (lrp1)对星形胶质细胞线粒体转运的重要调控作用，揭示lrp1通过调节细胞葡萄糖代谢影响arf1乳酸化修饰，进而调控星形胶质细 …