LPS-Induced Formation of Immunoproteasomes: TNF-α and Nitric …
Stimulation of mouse macrophages with LPS leads to tumor necrosis factor (TNF-α) secretion and nitric oxide (NO) release at different times through independent signaling pathways. While the …
Necroptosis suppresses inflammation via termination of TNF- or LPS …
2015年1月23日 · Here we examine the inflammatory outcome of TNF- and lipopolysaccharide (LPS)-induced necroptosis and report that this mode of cell death resulted in a dramatic …
TNF-α Induction by LPS Is Regulated Posttranscriptionally via a Tpl2 ...
2000年12月22日 · Subcellular fractionation of LPS-stimulated macrophages revealed that LPS signals transduced by Tpl2 specifically promote the transport of TNF-α mRNA from the …
为啥分别用不同浓度的TNF-α和LPS诱导hacat细胞都刺激不出NO和TNF …
为了模拟免疫系统会感染的响应，可以用TNFa、IFNgamma、IL4、IL13、IL17A、IL17F等细胞因子刺激细胞，其中TNFa是单核细胞浸润表皮时产生的，在适应性免疫介入后，Th1响应（细 …
Lipopolysaccharide-Induced Tumor Necrosis Factor Alpha …
During gram-negative sepsis, human monocytes are triggered to produce large quantities of proinflammatory cytokines such as tumor necrosis factor alpha (TNF-α) in response to …
LPS诱导的TNF_a模型及其抑制剂 - 知乎 - 知乎专栏
1.提出了一个新的机制性的解释LPS（脂多糖）诱导的 TNF-α （肿瘤坏死因子α）的“疾病模型”，我不太确定在这里使用“疾病模型”是否恰当，或许也可以说为是一个新的机制性的解释LPS（脂 …
Suppression of LPS-Induced TNF-α Production in Macrophages
The production of TLR-dependent proinflammatory cytokines such as tumor necrosis factor–α (TNF-α) and macrophage inflammatory protein 1α (MIP-1α) is substantially suppressed in the …
LPS induces the interaction of a transcription factor, LPS-induced TNF …
2005年3月25日 · Previously, we identified a transcription factor, LPS-induced TNF-α factor (LITAF), that regulates TNF-α transcription. We now report the discovery and characterization …
LPS-induced TNF-α factor mediates pro-inflammatory and pro ... - PubMed
2015年12月8日 · Lipopolysaccharide (LPS) is currently considered one of the major players in non-alcoholic fatty liver disease (NAFLD) pathogenesis and progression. Here, we aim to …
Signaling pathways involved in LPS induced TNFalpha production in human ...
2010年1月8日 · In the first part of this study, we identified the TLR4 signalling pathways activated by LPS (NFkappaB and p38 MAP Kinase), which lead to the secretion of TNFalpha by mature …