Leucine-rich, glioma inactivated 1, also known as LGI1, is a protein which in humans is encoded by the LGI1 gene. [5] . It may be a metastasis suppressor. The leucine-rich glioma inactivated …

LGI1 (Leucine-rich glioma-inactivated 1) antibody encephalitis is an autoantibody mediated form of limbic encephalitis. It is the most common antibody-mediated encephalopathy in those over …

Dec 30, 2021 · Leucine-rich, glioma inactivated 1 (LGI1) is a secreted glycoprotein, mainly expressed in the brain, and involved in central nervous system development and physiology. …

Leucine-rich glioma-inactivated protein 1 (LGI1) antibodies are probably the most common cause of limbic encephalitis and the second most common cause of autoimmune encephalitis after …

The LGI1 gene provides instructions for making a protein called leucine-rich glioma inactivated 1 (Lgi1) or epitempin. This protein is found primarily in nerve cells (neurons) in the brain, …

Mar 30, 2025 · LGI1 (Leucine Rich Glioma Inactivated 1) is a Protein Coding gene. Diseases associated with LGI1 include Epilepsy, Familial Temporal Lobe, 1 and Autosomal Dominant …

Jan 7, 2024 · Clinical features of nine cases of leucine-rich glioma inactivated 1 protein antibody-associated encephalitis. Human Cerebrospinal Fluid Monoclonal LGI1 Autoantibodies …

LGI1, a secreted synaptic protein mutated to cause human partial epilepsy, regulates a seizure-induced circuit response by redistributing Kv4.2 channels to the neuronal surface in a …

Objective: To compare acute treatment responses and long-term outcome in leucine-rich glioma-inactivated 1 (LGI1) antibody encephalitis. Methods: Retrospective case series of 118 patients …

Dec 1, 2021 · In this review, we will focus on LGI1 binding partners, “A Disintegrin And Metalloprotease (ADAM) 22 and 23”, the complex they form at the synapse, and will discuss …