乳酸脱氢酶为含锌离子的金属蛋白，分子量为135-140kd，是糖无氧酵解及糖异生的重要酶系之一，可催化丙酸与l-乳酸之间的还原与氧化反应，也可催化相关的α-酮酸。ldh广泛存在于人体组织中，以肾脏含量最高，其次是心肌和骨肌。红细胞内ldh约为正常血清的100倍。

2023年5月1日 · Lactate dehydrogenase (LDH) is an important enzyme of the anaerobic metabolic pathway. It belongs to the class of oxidoreductases, with an enzyme commission number EC 1.1.1.27. The function of the enzyme is to catalyze the reversible conversion of lactate to pyruvate with the reduction of NAD+ to NADH and vice versa. [1] .

What is a lactate dehydrogenase (LDH) isoenzymes test? This test measures lactate dehydrogenase (LDH) isoenzymes in a sample of your blood. It's a general test that can help find out if you have tissue damage from disease or injury. It can also help show which organs and other tissues are likely to be damaged.

ldh是糖酵解的重要酶系之一，可催化丙酸与l-乳酸之间的还原氧化反应，也可催化相关的α-酮酸。ldh主要存在于心肌、肝、肾、骨骼肌和肺等组织中。红细胞内ldh约为正常血清的100倍。 ldh有ldha、ldhb、ldhc三种亚基，可构成6种四聚体同工酶。

2021年1月13日 · LDH-4: Pancreas, kidney, and placenta; LDH-5: Liver and muscles; An increase in one type of isoenzyme may indicate an injury in the corresponding area; if you have increased LDH-3, your doctor will probably take a closer look at your lungs. If your LDH-5 is high, that may indicate liver damage.

2015年3月1日 · Lactate dehydrogenase 5 (LDH-5) catalyzes the reduction of pyruvate by NADH to form lactate, thus determining the availability of NAD to maintain the continuity of glycolysis. It is therefore an important control point in the system of cellular energy release. Its upregulation is common in many malignant tumors.

Background/aims: Lactate dehydrogenase-5 (LDH-5), an isoenzyme composed of 4 M-polypeptide chains, catalyzes the conversion of pyruvate to lactate with an unparalleled efficiency (anaerobic oxidation), but this function of LDH gradually fades away as the number of H over M chains increases.

2003年8月26日 · Lactate dehydrogenase-5 (LDH-5) catalyses the reversible transformation of pyruvate to lactate, having a principal position in the anaerobic cellular metabolism....

Background: Lactate-dehydrogenase-5 (LDH-5) is an important isoenzyme converting pyruvate to lactate under hypoxic conditions and might play an important role in the development and progression of malignancies. However, the role of LDH-5 in gastric cancer is still unclear.

乳酸脱氢酶有5种同工酶形式，即ldh1、ldh2、ldh3、ldh4、ldh5，可用电泳法进行分离。 人体心肌、肾、红细胞以LDH1和LDH2为最多。 肝和横纹肌则以LDH4和LDH5为主。