A kinesin is a protein complex belonging to a class of motor proteins found in eukaryotic cells. Kinesins move along microtubule (MT) filaments and are powered by the hydrolysis of adenosine triphosphate (ATP) (thus kinesins are ATPases, a type of enzyme).

驱动蛋白（Kinesin）是一条长80nm的杆状结构，头部一端有两个成球状的马达结构域，另一端是重链(kinesin heavy chain，KHC）和轻链(kinesin light chain，KLC）组成的扇形尾端，中间是重链组成的杆状区。

驱动蛋白（英語： Kinesin ）是一类蛋白质超级家族，属于分子马达的一种，其成员代表驱动蛋白-1（ Kinesin-1 ）在1985年被发现。 驱动蛋白是由单体组成的多聚体，其“头部”具有 ATP酶 活性 [ 1 ] ，能通过水解 ATP 获得能量，改变构型，进行运动。

2024年10月11日 · Kinesins are a diverse superfamily of microtubule-based motors that perform fundamental roles in intracellular transport, cytoskeletal dynamics and cell division.

与微管结合而起运输作用的 马达蛋白 有两大类：驱动蛋白kinesin， 动力蛋白 dynein，两者均需ATP提供能量。 Kinesin发现于1985年，是由两条轻链和两条重链构成的 四聚体，外观具有两个球形的头（具有ATP酶活性）、一个螺旋状的杆和两个扇子状的尾。 通过结合和水解ATP，导致颈部发生构象改变，使两个头部交替与微管结合，从而沿微管“行走”，将“尾部”结合的“货物”（运输泡或 细胞器）转运到其它地方。据估计哺乳动物中类似于kinesin的蛋白（KLP, kinesin-like protein …

2009年10月1日 · Kinesin superfamily proteins (also known as KIFs) are important molecular motors that directionally transport various cargos, including membranous organelles, protein complexes and mRNAs.

Most kinesins contain: (1) a catalytic domain (also known as a motor or head domain) responsible for nucleotide catalysis, microtubule binding, and force production, (2) a central α-helical stalk domain involved in coiled–coil interactions to organize the motor into higher order oligomers (e.g., dimers, tetramers), and (3) a tail domain ...

2023年7月19日 · Kinesins are biological motor proteins that are ATP-dependent and function to assist cells with the transport of molecules along microtubules. Simply put, these proteins, function as highways...

There are currently 14 groups and many ungrouped or orphan kinesins. Among these, three kinesins – kinesin-1, kinesin-14 and kinesin-13 – highlight the diverse structure and function of the family. Kinesin-1, the first-discovered kinesin, has been studied extensively.

驱动蛋白（kinesins）是一类体积只有几十纳米的“分子马达”（分子发动机），是1985年从鱿鱼的轴质（axonplasm）中分离的一种发动机蛋白。 用低角度旋转投影电子显示技术观察结果显示，驱动蛋白是一条长80nm的杆状结构，头部一端有两个成球状的马达结构域，另一端是重链（kinesin heavy chain，KHC）和轻链（kinesin light chain，KLC）组成的扇形尾端，中间是重链组成的杆状区。 球状的头部具有ATP结合部位和微管结合部位。 驱动蛋白穿行在细胞里的微管“轨道”上， …