The Ki-67 protein (also known as MKI67) is a cellular marker for proliferation, [10] and can be used in immunohistochemistry. It is strictly associated with cell proliferation.

2025年3月17日 · Ki-67 is a protein found in the nucleus of cancer cells that are actively growing and dividing. For breast cancer, Ki-67 is one of the main tumor biomarkers that your healthcare provider will check for when diagnosing, staging, and monitoring the cancer.

2024年10月23日 · The KI-67 protein test is a diagnostic tool used in the field of oncology to measure the level of a protein called KI-67 in cancer cells. The KI-67 protein is a marker for cell proliferation, meaning it indicates how quickly cancer cells are dividing and growing.

2022年3月14日 · Her tumor had a higher level of a cancer-related gene known as Ki-67, indicating rapid reproduction of cancer cells. A mixed bag of clinical trial data has shown that certain levels of Ki-67 in breast tumors support better outcomes for patients who are treated with CDK inhibitors.

A Ki-67 proliferation index over 30% is typically considered high. The Ki-67 proliferation index may be used to help predict how well some cancers, such as breast cancer, will respond to certain treatments, such as chemotherapy. Also called Ki-67 score.

Lower Ki 67 levels may indicate a better response to hormone therapies, while higher Ki 67 levels may warrant more aggressive treatment options. Overall, Ki 67 plays a crucial role in assessing tumor growth rate and predicting prognosis in breast cancer.

2025年2月20日 · Generally speaking, Ki-67 levels over 14% to 25% are considered high (depending on breast cancer and biopsy type) whereas levels over 40% are considered very high. High Ki-67 has been linked to unfavorable breast cancer outcomes in …

The identification of Ki-67 in tissue samples serves as a valuable biomarker for gauging the growth fraction of a tumor. As breast cancer often presents in various forms and with differing growth rates, the Ki-67 score offers a measurable indicator that correlates with tumor aggressiveness.

2024年1月31日 · The Ki-67 test is used in breast cancer to measure the rate of cell proliferation or growth in tumor tissues.

A way to measure how fast cancer cells in a tumor are dividing. Ki-67 is a protein that is found only in cells that are dividing. A high Ki-67 score means many cells are dividing quickly and that the cancer is likely to grow and spread. A Ki-67 score over 30% is typically considered high.