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Structural basis for activation and filamentation of glutaminase
2023年10月13日 · Glutaminase catalyzes the first step of glutamine metabolism, converting glutamine to glutamate, which enters the tricarboxylic acid cycle. In human, glutaminase is encoded by two different...
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Driver Side Inner LH Tail Light For Ford Escape Kuga 2017 2018 …
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Distribution and localization of a G protein-coupled inwardly ...
1994年7月11日 · KGA was originally cloned from the heart and represents the first G protein-activated K + channel identified. It is expressed in peripheral tissue solely in the atrium, but not in the ventricle, skeletal muscle, lung and kidney.
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Novel 1,3,4-Selenadiazole-Containing Kidney-Type Glutaminase …
2018年12月13日 · Kidney-type glutaminase [KGA/isoenzyme glutaminase C (GAC)] is becoming an important tumor metabolism target in cancer chemotherapy. Its allosteric inhibitor, CB839, showed early promise in cancer therapeutics but limited efficacy in in vivo cancer models.