2023年6月15日 · KAT6A syndrome is an extremely rare genetic neurodevelopmental disorder in which there is a variation (mutation) in the KAT6A gene. Variations in the KAT6A gene can …

KAT6A syndrome, also known as Arboleda-Tham Syndrome (ARTHS), is a rare disorder resulting from a mutation in the KAT6A gene. Through genetic research, we have learned that the …

Arboleda-Tham syndrome (ARTHS), [10] also referred to as KAT6A Syndrome (Arboleda-Tham Syndrome), is a rare autosomal dominant developmental disorder, caused by various …

The KAT6 Foundation supports people and their families who are living with KAT6A and KAT6B syndromes around the world. We advance scientific research aimed at developing treatments …

2025年3月30日 · KAT6A (Lysine Acetyltransferase 6A) is a Protein Coding gene. Diseases associated with KAT6A include Arboleda-Tham Syndrome and Syndromic Intellectual …

What is KAT6A syndrome? KAT6A syndrome is a rare genetic condition that results from ‘spelling mistakes’ (aka mutations) in a gene called KAT6A. (The KAT6A gene is located on the short …

2025年1月6日 · KAT6A is an oncogene in human acute myeloid leukemia (AML), and KAT6A overexpression in AML is associated with metastases and poor prognoses. Furthermore, …

Studying KAT6A and KAT6B gene function will increase our overall knowledge of multiple systems in the body to unlock the possibility for greater health for all. Children with KAT6 …

In the current review, we discuss the physiological functions of the acetyltransferases KAT6A and KAT6B as well as their functions under pathological conditions of aberrant expression, leading …

2018年8月1日 · Here we present highly potent, selective inhibitors of KAT6A and KAT6B, denoted WM-8014 and WM-1119. Biochemical and structural studies demonstrate that these …