ITGB4 Gene - GeneCards | ITB4 Protein | ITB4 Antibody
2025年3月30日 · ITGB4 (Integrin Subunit Beta 4) is a Protein Coding gene. Diseases associated with ITGB4 include Epidermolysis Bullosa, Junctional 5B, With Pyloric Atresia and …
Integrin beta 4 - Wikipedia
Integrin, beta 4 (ITGB4) also known as CD104 (C luster of D ifferentiation 104), is a human gene. [5] Integrins are heterodimers composed of alpha and beta subunits, that are noncovalently …
整合素亚基β4（ITGB4）基因 | MCE - MCE-生物活性分子大师
该基因编码整合素β4 亚基，层粘连蛋白的受体。 该亚基倾向于与 alpha 6 亚基结合，并可能在浸润性癌的生物学中发挥关键作用。 该基因的突变与伴有幽门闭锁的大疱性表皮松解有关。 已 …
Integrin β4 promotes cell invasion and epithelial-mesenchymal ...
2017年1月13日 · Integrin β4 (ITGB4) is a transmembrane receptor involved in tumorigenesis and the invasiveness of many cancers. However, its role in hepatocellular carcinoma (HCC), one …
Integrin β4-Targeted Cancer Immunotherapies Inhibit Tumor Growth …
2020年2月15日 · Integrin β4 (ITGB4) has been shown to play an important role in the regulation of cancer stem cells (CSC). Immune targeting of ITGB4 represents a novel approach to target …
The mechanism of ITGB4 in tumor migration and invasion
2024年8月6日 · Integrin β4 (ITGB4) is a transmembrane protein that functions as a mechanosensor, mediating the bidirectional exchange of information between the intracellular …
ITGB4 integrin subunit beta 4 [ (human)] - National Center for ...
ITGB4 is overexpressed in hepatocellular carcinoma tissues and promotes metastases of HCC by conferring anchorage independence through EGFR-dependent FAK-AKT activation. High …
Integrin β4 in Breast Cancer A Focused Review
This review broadly summarizes current research on ITGB4’s involvement in breast cancer, focusing on its role in metastasis, metabolic reprogramming, drug resistance, and …
ITGB4 - 百度百科
ITGB4是位于17号染色体的 基因。 整联蛋白是由α和β亚基组成的异二聚体，它们是非共价结合的跨膜糖蛋白受体。 α和β多肽的不同组合形成复合物，它们的配体结合特异性不同。 整联蛋白 …
ITGB4 gene - MedlinePlus
The ITGB4 gene provides instructions for making one part (the β4 subunit) of a protein known as an integrin. Integrins are a group of proteins that regulate the attachment of cells to one …