The interferon stimulated gene 54 promotes apoptosis - PubMed
2011年3月4日 · In this report we demonstrate that ISG54, also known as IFN-induced protein with tetratricopeptide repeats 2 (IFIT2), is a mediator of apoptosis. Expression of ISG54, …
Crystal structure of ISG54 reveals a novel RNA binding structure …
2012年7月24日 · Here, we present the crystal structure of ISG54, an ISG56 family protein with a novel RNA-binding structure. The structure shows that ISG54 monomers have 9 …
A Death-Promoting Role for ISG54/IFIT2 - PMC - PubMed Central …
One of the primary response genes induced after an infection or treatment with type I or III IFN is known as IFN-stimulated gene 54 (ISG54) or IFN-induced gene with tetratricopeptide repeats …
The Interferon Stimulated Gene 54 Promotes Apoptosis
In this report we demonstrate that ISG54, also known as IFN-induced protein with tetratricopeptide repeats 2 (IFIT2), is a mediator of apoptosis. Expression of ISG54, …
重大进展！山东大学赵伟团队发现干扰素刺激基因激活的新机制|脂 …
2020年6月22日 · 近日，山东大学赵伟团队在 Nature Immunology 在线发表题为“ Redox homeostasis maintained by GPX4 facilitates STING activation ”的研究论文，该研究显示了 谷 …
ISG54 and ISG56 are induced by TLR3 signaling in U373MG …
2014年7月1日 · ISG54 and ISG56 encode proteins containing multiple tetratricopeptide repeat motifs, which mediate a variety of protein–protein and protein–RNA interactions (Sen and …
生物物理所等在抗病毒蛋白结构与功能研究方面取得新进展----中 …
2012年7月27日 · 刘迎芳课题组通过解析晶体结构，发现ISG54具有一种全新的RNA结合蛋白结构，该结构含有9个tetratricopeptide repeat-like结构域，形成domain-swapped二体（如图）。 …
Crystal structure of IFIT2 (ISG54) predicts functional properties of ...
2012年9月11日 · The first crystal structure of an IFIT protein, the human ISG54 (IFIT2), reveals that the protein exists as domain-swapped dimer and each subunit has 9 helix-turn-helix TPR …
Interferon-Induced Ifit2/ISG54 Protects Mice from Lethal VSV
2012年5月17日 · A prominent family of ISGs is the interferon-induced with tetratricopeptide repeats (Ifit) genes comprising three members in mice, Ifit1/ISG56, Ifit2/ISG54 and Ifit3/ISG49. …
A death-promoting role for ISG54/IFIT2 - PubMed
One of the primary response genes induced after an infection or treatment with type I or III IFN is known as IFN-stimulated gene 54 (ISG54) or IFN-induced gene with tetratricopeptide repeats …