Chapter 12 Quiz - Neurons Flashcards | Quizlet
Hole's Human Anatomy and Physiology 15th Edition • ISBN: 9781259864568 (11 more) David Shier, Jackie Butler, Ricki Lewis
Axon initial segments: structure, function, and disease - PMC
The axon initial segment (AIS) is located at the proximal axon and is the site of action potential initiation. This reflects the high density of ion channels found at the AIS. Adaptive changes to the location and length of the AIS can fine-tune the ...
Immunoproximity biotinylation reveals the axon initial segment …
2023年12月11日 · The axon initial segment (AIS) is the 20–60 µm long proximal region of the axon responsible for action potential generation and maintenance of neuronal polarity 1,2.
The Axon Initial Segment: An Updated Viewpoint
2018年2月28日 · Between the cell body and the axon sits a unique compartment called the axon initial segment (AIS). The AIS was first described 50 years ago (Palay et al., 1968), and its molecular composition and organization have been progressively elucidated during the following decades (Rasband, 2010a).
Axon Initial Segment Structure and Function in Health and Disease
2024年10月31日 · The AIS, as its name implies, is often contained to the first section of axon abutted to the soma and is home to a dizzying array of ion channels, attendant scaffolding proteins, intracellular organelles, extracellular proteins, and, in some cases, synapses.
Short- and Long-Term Plasticity at the Axon Initial Segment
2011年11月9日 · The majority of neurons are polarized into dendrites that receive synaptic input and axons that transmit action potential output. The length of the axon immediately distal to the axon hillock, termed the axon initial segment (AIS), separates these two regions and serves multiple neuronal functions.
Location of the axon initial segment assembly can be predicted …
2024年3月15日 · The axon-soma boundary is marked by a unique structural feature called the axon initial segment (AIS), which is usually 20–60 μm in length and located along the proximal axon in most neurons. The AIS is characterized by specific cytoskeletal adaptors, scaffold proteins, membrane adhesion molecules, and voltage-gated ion channels.
Imaging of the Axon Initiation Segment - PMC - PubMed Central …
The axon initial segment (AIS) is the first 20–60 μm segment of the axon proximal to the soma of the neuron. ... image processing algorithm targeted to multicellular fluorescent images of neurons and designed to extract and label centerline traces of each neurite in the image (Kayasandik, Negi, Laezza, Papadakis, & Labate, 2018). As in basic ...
Electrogenic Tuning of the Axon Initial Segment - PMC
Where exactly these signals are initiated in neurons has been a basic question in neurobiology and the subject of extensive study. Converging lines of evidence indicate that APs are initiated in a discrete and highly specialized portion of the axon—the axon initial segment (AIS).
An axon initial segment is required for temporal precision in …
Central neurons initiate action potentials (APs) in the axon initial segment (AIS), a compartment characterized by a high concentration of voltage-dependent ion channels and specialized cytoskeletal anchoring proteins arranged in a regular nanoscale pattern.
- 某些结果已被删除