吲羟（英文名称indoxyl）又名3-羟基吲哚，3-吲哚酚（3-hydroxyindole）；β-羟基吲哚(β-hydroxyindole)，无色或黄色柱状结晶，蒸气有粪便的气味。 易溶于丙酮，能溶于水、乙醇、 …

Indoxyl sulfate, also known as 3-indoxylsulfate and 3-indoxylsulfuric acid, is a metabolite of dietary L-tryptophan that acts as a cardiotoxin and uremic toxin. [1] [2] [3] High concentrations of …

In organic chemistry, indoxyl is a nitrogenous substance with the chemical formula: C 8 H 7 NO. [1] [2] Indoxyl is isomeric with oxindol and is obtained as an oily liquid.

Indoxyl sulfate is an extensively studied uremic solute. It is a small molecule that is more than 90% bound to plasma proteins. Indoxyl sulfate is derived from the breakdown of tryptophan by …

2016年11月30日 · Indoxyl sulfate has been most frequently implicated as a contributor to renal disease progression and vascular disease. Studies have suggested that indoxyl sulfate also …

2021年10月25日 · Indoxyl sulfate (IS), results from the sulfonation of bacterially-derived indole via sulfotransferases in human liver 16; however, the rate of indoxyl sulfate production is driven by …

Indoxyl is a member of the class of hydroxyindoles that is 1H-indole substituted by a hydroxy group at position 3. It is a member of hydroxyindoles and a heteroaryl hydroxy compound.

Indoxyl sulfate (IS), a uremic toxin, causes chronic kidney disease (CKD) progression via its tubulotoxicity. After cellular uptake, IS directly induces apoptotic and necrotic cell death of …

Indican (Indoxyl-β-D-glucoside), a glycoside of indoxyl, is a precursor of the dyesindigo and indirubin. Indican has a major metabolite, indoxyl sulfate (IS). IS, an uremic toxin, is a …

Indoxyl sulfate signals for rapid mRNA stabilization of Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2 (CITED2) and suppresses the expression of hypoxia …