Indole is an organic compound with the formula C6H4CCNH3. Indole is classified as an aromatic heterocycle. It has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered pyrrole ring. Indoles are derivatives of indole where one or more of the hydrogen atoms have been replaced by substituent groups.

吲哚丁酸是一种有机化合物，化学式为C12H13NO2，外观为白色结晶固体，难溶于水。 纯品为白色至淡黄色 结晶固体，原药为白色至浅黄色结晶。 熔点124～125℃（纯品）；121～124℃（原药）℃. 溶解度 水中 (20℃)50mg/L，苯＞1000， 丙酮 、乙醇、 乙醚 为30～100， 氯仿 0.01～0.1 (均为g/L)，在中性、酸性介质中稳定。 本品对酸稳定，在 碱金属 的 氢氧化物 和 碳酸 化合物的溶液中则成盐。 毒性LD50 (mg/kg)： 小白鼠 急性经口100mg/kg， 鲤 鱼TLm (48h)180mg/L。 …

An indolyl group is defined as a 1-ethyl-indolyl group linked at the 5-position on a pyrimidine backbone, which is crucial for antiproliferative activity in the context of chemistry. You might find these chapters and articles relevant to this topic.

2015年1月28日 · Sulfonated-β-cyclodextrin (β-CD-SO 3H) promoted efficient and fast electrophilic substitution reaction of indoles with various isatins reflux in water is reported affording various 3-indolyl-3-hydroxy oxindoles and 3,3-di (indolyl)indolin-2-ones …

2019年8月14日 · 3-Alkylated indole cores have been found in countless natural products and many biologically active compounds, including pharmaceuticals. In this report, a highly efficient approach to C3-alkylated indole derivatives on DNA via indolyl alcohol formation followed by metal-free transfer hydrogenation is developed.

2024年9月17日 · Based on previous research, this study synthesized 24 compounds by splicing the substructures of the indolyl group and the isothiocyanate group. Alternaria alternata, Phytophthora capsici, Botrytis cinerea, and Valsa mali were used to test the activity of …

2024年1月11日 · This review centers on the synthetic strategies employed with indolyl-ynones. Indolyl-ynone, owing to its highly reactive ynone moiety, frequently partakes in dearomatizing spirocyclization reactions and subsequent rearrangement reactions when subjected to various reaction conditions.

2024年2月28日 · In view of reaction type, mechanism, and status, this review will cover the synthesis of indole and tryptophan C -heteroaryl glycosides with diverse regio- and diastereoselectivity from four perspectives which include a) conventional approach, b) heterocyclization and C -glycosylation sequence, c) metal …

2024年8月5日 · A new range of indolyl imine compounds was prepared by Schiff base reaction of indole-7-carbaldehhydes with aryl or heteroaryl aniline derivatives. Upon investigation of biological activity of the targeted indolyl imine analogous, it was observed that the compound 3e was determined as the most promising candidate for the α-glucosidase enzyme ...

2020年12月12日 · Indole is an important heterocyclic system that provides the skeleton to lysergic acid diethylamide (LSD), strychnine, and alkaloid obtained from plants. Physically, they are crystalline colorless in nature with specific odors.