Indole is an organic compound with the formula C 6 H 4 CCNH 3. Indole is classified as an aromatic heterocycle. It has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered pyrrole ring. Indoles are derivatives of indole where one or more of the hydrogen atoms have been replaced by substituent groups.

Indole | C8H7N | CID 798 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

The indole nucleus is an important element of many natural and synthetic molecules with significant biological activity. This review covers some of the relevant and recent achievements in the biological, chemical and pharmacological activity of ...

indole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.

2023年7月20日 · Specific indole molecules (derived in the gut from the breakdown of the glucobrassicin in cruciferous vegetables) that have shown estrogen-reducing effects in preclinical (animal and laboratory) studies are indole-3-carbinol (I3C) and 3,3'-diindolylmethane (DIM), according to the Micronutrient Information Center at Oregon State University (OSU ...

2025年1月10日 · Indole is a bicyclic compound, consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring. This structure imparts indole with a planar configuration, allowing for extensive conjugation across the rings.

2023年12月21日 · Indole is a signalling molecule produced both by bacteria and plants. In this review its signalling role between microbes and in particular in the human gut is discussed. Besides the natural roles, indole also has value for flavour and fragrance applications, for example, in food industry or perfumery.

2024年4月22日 · Indole is a weak acid (with a value of pK a = 16.97), with an acidity comparable to pyrrole, and to aliphatic alcohols. It can be converted to the N -sodium derivative, in liquid ammonia, or with sodium hydride (NaH) in an organic solvent.

Indole is a chemically important nucleus that exhibits diverse biological activity and is the basis for various derivatives with different biological activities. From: European Journal of Medicinal Chemistry, 2017

In plants, indole is primarily known for its role in the synthesis of indole-3-acetic acid, one of the most important plant hormones. IAA regulates several critical plant functions, including cell elongation, root development, and response to environmental stimuli.