IL-7和IL-7R的生物学和临床应用 - 知乎
本文综述了IL-7和IL-7R的生理学和病理学，以及利用靶向IL-7/IL-7R信号以获得治疗益处的机会和前景。 虽然高水平的IL-7 mRNA是首先在胸腺中检测到的，但最新的研究和大量报告表明， …
IL7R Gene - GeneCards | IL7RA Protein | IL7RA Antibody
Mar 30, 2025 · IL7R (Interleukin 7 Receptor) is a Protein Coding gene. Diseases associated with IL7R include Immunodeficiency 104, Severe Combined and T-B+ Severe Combined …
Interleukin-7 receptor - Wikipedia
Interleukin-7 receptor is expressed on various cell types, including naive and memory T cells and many others. Interleukin-7 receptor has been shown to play a critical role in the development …
Flip the coin: IL-7 and IL-7R in health and disease - Nature
Nov 19, 2019 · In this Review, we examine the physiology and pathophysiology of IL-7 and IL-7R, with particular emphasis on their involvement in the promotion of cancer, for which there is …
白介素-7受体 - 维基百科，自由的百科全书
白细胞介素-7受体 （Interleukin-7 receptor，IL7R），简称 白介素-7受体，是一种 I型细胞因子受体，能结合 白细胞介素-7 （IL7）。 它由 白介素-7受体α亚基 （CD127）与 γ亚基 （CD132） …
健康与疾病中的IL-7和IL-7R - 知乎
IL-7和IL-7R参与结肠慢性炎症与以下观点一致：转移性结直肠癌患者显示高IL-7水平，并且癌组织本身可以分泌IL-7。 IL-7R介导的实体癌中潜在的促肿瘤功能。 体外和体内研究表明，IL-7–IL …
The Role of IL-7 and IL-7R in Cancer Pathophysiology and …
IL-7 plays a vital role in T-cell development, proliferation, and differentiation, as well as in B cell maturation through the activation of the IL-7 receptor (IL-7R). IL-7 is closely associated with …
白细胞介素7受体α亚基CD127 - mabnus.cn
May 21, 2024 · CD127是白介素7受体α亚基（IL-7Rα），除此之外，它还充当胸腺基质淋巴细胞生成素（TSLP）的受体。 CD127在调节免疫细胞的增殖、分化和存活，特别是在淋巴细胞的发 …
IL7R gene: MedlinePlus Genetics
The IL7R gene provides instructions for making a protein called interleukin 7 (IL-7) receptor alpha chain. This protein is one piece of both the IL-7 receptor and the thymic stromal lymphopoietin …
Interleukin-7 receptor-α - Wikipedia
Interleukin-7 receptor subunit alpha (IL7R-α) also known as CD127 (C luster of D ifferentiation 127) is a protein that in humans is encoded by the IL7R gene. [5][6] IL7R-α is a type I cytokine …