2019年11月19日 · IL-7 is a 25 kDa secreted soluble globular protein encoded by the IL7 gene. Its receptor (IL-7R) is a heterodimeric complex consisting of IL-7Rα (encoded by IL7R) and the …

Interleukin-7 (IL-7) is a multipotent cytokine that maintains the homeostasis of the immune system. IL-7 plays a vital role in T-cell development, proliferation, and differentiation, as well …

Overview: IL-7 is a member of the family of cytokines with four anti-parallel α helixes that bind Type I cytokine receptors. It is produced by stromal cells and is required for development and …

2024年12月25日 · IL7 (Interleukin 7) is a Protein Coding gene. Diseases associated with IL7 include Epidermodysplasia Verruciformis 5 and Inherited Epidermodysplasia Verruciformis. …

Interleukin-7 (IL-7) is a non-hematopoietic cell-derived cytokine with a central role in the adaptive immune system. It promotes lymphocyte development in the thymus and maintains survival of …

2021年12月1日 · IL-7 contributes to host defense by regulating the development and homeostasis of immune cells, including T lymphocytes, B lymphocytes, and natural killer (NK) cells. Clinical …

2025年3月8日 · IL7 plays an essential role in lymphoid cell survival, and in the maintenance of naive and memory T cells. Alternative splicing results in multiple transcript variants encoding …

2021年12月2日 · Interleukin-7 (IL-7), a molecule known for its growth-promoting effects on progenitors of B cells, remains one of the most extensively studied cytokines. It plays a vital …

IL-7’s essential properties as a required factor for lymphocyte development and modulator of T cell homeostasis make it an attractive candidate for modulating immunodeficiency and …

2022年12月1日 · Review covers sources of IL-7 and responses to it, abnormalities in disease and therapeutic applications. IL-7 is a member of the family of cytokines with four anti-parallel α …