IL6R Gene - GeneCards | IL6RA Protein | IL6RA Antibody
2025年3月30日 · IL6R (Interleukin 6 Receptor) is a Protein Coding gene. Diseases associated with IL6R include Hyper-Ige Syndrome 5, Autosomal Recessive, With Recurrent Infections and …
Interleukin-6 receptor - Wikipedia
Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. Dysregulated production of IL6 and this receptor …
IL6RA, Interleukin-6 Receptor Subunit Alpha | SpringerLink
The interleukin-6 receptor (IL-6R) is a type I transmembrane protein that was cloned and described in 1988 (Yamasaki et al. 1988). It serves as the non-signaling alpha-receptor of the …
【Cell论文拆解】小鼠模型中应激诱导的IL-6的起源和功能 - 知乎
白介素6 （IL-6）属于多效细胞因子，可促进T细胞群体扩增和活化以及B细胞分化，调节急性期反应。 人们已知心理压力会诱导内分泌IL-6，并已在大鼠，小鼠和人类中被证明。 但 急性应激 …
Il6ra interleukin 6 receptor, alpha [ (house mouse)]
2025年2月11日 · IL6Ralpha function in myeloid cells modulates the inflammatory response during irritant contact dermatitis. Repopulating Microglia Promote Brain Repair in an IL-6-Dependent …
Signaling by IL-6 promotes alternative activation of ... - Nature
2014年3月30日 · Il6ra Δmyel mice were resistant to IL-4-mediated alternative polarization of macrophages and exhibited enhanced susceptibility to lipopolysaccharide (LPS)-induced …
西湖大学李波团队揭示脑干最后区IL-6信号介导肿瘤恶病质的神经 …
2024年6月13日 · 敲低Il6ra显著延长肿瘤恶病质小鼠寿命，缓解其体重降低水平，提高摄食、摄水量（图3c-h）；研究人员还引入另一种肿瘤恶病质模型——胰腺导管腺癌（PDAC）模型，得 …
IL-6/Stat3-Dependent Induction of a Distinct, Obesity ... - Cell Press
2017年7月5日 · In the current study we identify both in obese mice and humans that NK cells upregulate interleukin-6 receptor (IL6Ra) and colony-stimulating-factor 1 receptor (Csf1r) …
内毒素介导因子之IL-6的受体及其信号转导 - 知乎
小鼠IL-6Rα链是460个氨基酸的多肽，结构与人α链相同。 具有典型的“细胞因子家族结构域”，即4个保守 半胱氨酸 残基和WSXWS模体（W代表色氨酸、S代表 丝氨酸，X代表任何氨基 …
UniProt
Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation leads to the regulation of …