Interleukin 6 receptor (IL6R) also known as CD126 (C luster of D ifferentiation 126) is a type I cytokine receptor. Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth …

2025年3月30日 · IL6R (Interleukin 6 Receptor) is a Protein Coding gene. Diseases associated with IL6R include Hyper-Ige Syndrome 5, Autosomal Recessive, With Recurrent Infections and …

2017年1月6日 · Signaling of the cytokine interleukin-6 (IL-6) via its soluble IL-6 receptor (sIL-6R) is responsible for the proinflammatory properties of IL-6 and constitutes an attractive …

The interleukin-6 receptor (IL-6R) is a type I transmembrane protein that was cloned and described in 1988 (Yamasaki et al. 1988). It serves as the non-signaling alpha-receptor of the …

2020年7月12日 · The IL6R gene encodes the alpha subunit of the IL6 receptor. This subunit binds IL6 directly. The other subunit, gp130 (IL6ST; 600694), is responsible for intracellular signal …

Interleukin-6 Receptor (IL-6R) Expression in Human Gastric Carcinoma and its Clinical Significance. The aim of the study is to analyse the expression of Interleukin-6 receptor in …

IL6R is a prognostic marker in Kidney renal clear cell carcinoma, Pancreatic adenocarcinoma

2024年6月19日 · Interleukin-6 (IL6) is crucial in regulating the inflammatory cascade, but the causal link between IL6 signaling downregulation and respiratory diseases risk is unclear. This …

2020年2月15日 · IL-6 binds to the IL-6R α-chain (IL-6Rα) and signals via the signal transducer gp130. Recently, IL-6 was found to also bind to the cell surface glycoprotein CD5, which would …

2024年12月19日 · Evidence for the role of IL6 and its cognate receptor (IL6R) within the tumour itself and surrounding microenvironment remains a key area of research. IL6R can be …