Dec 7, 2023 · Learn how Microsoft meets Department of Defense (DoD) Impact Level 5 (IL5) standards.

Interleukin 5 (IL-5) is an interleukin produced by type-2 T helper cells and mast cells. Through binding to the interleukin-5 receptor, interleukin 5 stimulates B cell growth and increases immunoglobulin secretion—primarily IgA. It is also a key mediator in eosinophil activation.

Feb 22, 2024 · IL5 — IL5 includes higher sensitivity CUI, Mission Critical Information, and NSS. IL5 exists within a narrow category between IL4 and IL6, but it is distinguishable by the inclusion of NSS. DoD ILs are useful labels for a comprehensive security categorization system.

Apr 19, 2024 · What is DoD IL5? The DoD’s IL5 plays a crucial role in protecting information systems that process, store, or transmit information that, if compromised, could cause ‘catastrophic harm’ to national security.

IL-5 is produced by both hematopoietic and non-hematopoietic cells including T cells, granulocytes, and natural helper cells. IL-5 exerts its effects for proliferation and differentiation via receptors that comprise an IL-5-specific α and common β-subunit.

IL5: Adds stricter controls for CUI and data in unclassified national security systems, requiring moderate confidentiality and moderate integrity. IL6: Reserved for handling classified information up to the secret level, requiring the highest level of security controls.

While interleukin-5 (IL-5) is initially identified by its ability to support the growth and terminal differentiation of mouse B cells in vitro into antibody-secreting cells, recombinant IL-5 exerts pleiotropic activities on various target cells including B cells, eosinophils, and basophils.

Interleukin-5 (IL-5) exerts a central pathogenic role in differentiation, recruitment, survival, and degranulation of eosinophils.

The interleukin 5 (colony-stimulating factor, eosinophil) (IL5) gene includes three introns and has numerous repetitive sequences. A common possible regulatory element, including a conserved decamer, lies adjacent to the TATA boxes (5′-TATAAA-3′) upstream of …

Dec 25, 2024 · IL5 (Interleukin 5) is a Protein Coding gene. Diseases associated with IL5 include Allergic Disease and Pulmonary Eosinophilia. Among its related pathways are MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway. Gene Ontology (GO) annotations related to this gene include cytokine activity and interleukin-5 receptor binding.