
免疫调节达人之细胞因子— IL-4 - 知乎 - 知乎专栏
IL-4 促进 B 细胞 MHCⅡ类抗原、FcεRⅡ/CD23 和 CD40 的表达,并增强 B 细胞提呈抗原能力,使免疫系统对小量抗原刺激发生免疫应答。 增加 FcεRⅡ/CD23 (IgE Fc 段低亲和力受体) 的 …
Recent advances in understanding the role of IL-4 signaling
IL-4 induces elevated cell surface expression of CD23 (the low-affinity IgE receptor) on B cells and of class II major histocompatibility complex (MHC) molecules. In addition, IL-4 acts as a T …
免疫调节因子-IL-4 - 知乎 - 知乎专栏
IL-4促进B细胞MHCⅡ类抗原、 FcεRⅡ/CD23 和 CD40 的表达,并增强B细胞提呈抗原能力,使免疫系统对小量抗原刺激发生免疫应答。 增加FcεRⅡ/CD23 (IgE Fc 段低亲和力受体) 的表达, …
白细胞介素-4 (IL-4) | 重组蛋白 | MCE - MCE-生物活性分子 ...
Specifically, IL-4 is involved in regulating the differentiation of antigen-stimulated naive T cells to produce IL-4 and other cytokines, including IL-5, IL-10, and IL-13. At the same time, it also …
STAT3 determines IL-4 signalling outcomes in naïve T cells
2021年5月18日 · Mounting evidence indicates that cells can dynamically alter their IL-4/IL-13 receptor signature to modulate downstream immune outcomes upon pathogen encounter. …
IL-4 drives exhaustion of CD8 + CART cells - Nature
2024年9月12日 · Further, IL-4-treated CD8 + CART cells develop signs of exhaustion independently of the presence of CD4 + CART cells. Conversely, IL-4 pathway editing or the …
Regulation of IL4 gene expression by T cells and therapeutic ...
2003年7月1日 · Interleukin-4 (IL-4) is crucial for the differentiation of naive T helper (T H) cells into the T H 2 effector cells that promote humoral (antibody) immunity and provide...
CD4+/IL‑4+ lymphocytes of the lamina propria and substance P …
Moreover, it was found that acute stress caused a shift towards a predominantly anti‑inflammatory immune response (T helper 2 cells), as shown by the increase in the percentage of CD4 + …
白细胞介素 4(IL-4) - 丁香通研选
2017年8月31日 · IL-4 促进 B 细胞 MHCⅡ类抗原、FcεRⅡ/CD23 和 CD40 的表达,并增强 B 细胞提呈抗原能力,使免疫系统对小量抗原刺激发生免疫应答。 增加 FcεRⅡ/CD23 (IgE Fc 段低 …
白细胞介素4(IL-4)你了解多少? - 知乎
2021年7月21日 · 白细胞介素-4(il-4)是一种糖基化的i型细胞因子,具有三个链内二硫键,采用捆绑式四α螺旋结构。由th2偏向的cd4+t细胞、肥大细胞、嗜碱性粒细胞和嗜酸性粒细胞表达。