免疫研究热门靶点之IL2Rg - 知乎 - 知乎专栏
白介素2受体γ链 （interleukin 2 receptor subunit gamma chain, IL2Rg，或CD132），是多种重要免疫因子的共同受体亚基，包括IL-2、IL-4、IL-7、IL-9、IL-15和IL-21，因此，也被称为受体 …
Common gamma chain - Wikipedia
The common gamma chain (γ c) (or CD132), also known as interleukin-2 receptor subunit gamma or IL-2RG, is a cytokine receptor sub-unit that is common to the receptor complexes for at …
IL2RG Gene - GeneCards | IL2RG Protein | IL2RG Antibody
2025年3月30日 · IL2RG (Interleukin 2 Receptor Subunit Gamma) is a Protein Coding gene. Diseases associated with IL2RG include Severe Combined Immunodeficiency, X-Linked and …
白介素2(IL-2)相关细胞因子及生物学功能 - 知乎
IL-2受体是由α、β、γ三条链组成的异聚体，即IL-2R由 IL-2Rα （CD25）、 IL-2Rβ （CD122）、 IL-2Rγ （CD132）组成。 其中β/γ为下游信号通路激活所必需，α则主要促进二者结合。 当IL-2 …
IL2RG interleukin 2 receptor subunit gamma [ (human)]
Data indicate a nonsense mutation in exon 8 (p.R328X) of interleukin (IL)-2 receptor common gamma chain gene (IL2RG)in two brothers were diagnosed with X-Linked combined …
IL2RG interleukin 2 receptor subunit gamma - NIH Genetic Testing ...
2025年2月8日 · Clinical resource with information about IL2RG, Combined immunodeficiency, X-linked, X-linked severe combined immunodeficiency, and available tests. There are links to …
IL2RG gene - MedlinePlus
The IL2RG gene provides instructions for making a protein called the common gamma chain. This protein is a component of several different receptors that are involved in immune system …
IL2RG: A series of three novel mutations with clinical manifestations
2016年5月19日 · The IL2RG gene encodes the γ c portion of the IL-2 receptor, which along with IL-2Rα and IL-2Rβ makes up the entire IL-2 receptor. The γ c portion interacts with the IL-2 …
白细胞介素 2 受体亚基γ（IL2RG）基因 - MCE-生物活性 ...
由该基因编码的蛋白质是许多白细胞介素受体的重要信号成分，包括白细胞介素-2、-4、-7 和-21，因此被称为共同γ链。 该基因的突变会导致 X 连锁严重联合免疫缺陷 (XSCID) 以及 X 连 …
Biology and regulation of IL-2: from molecular mechanisms to ... - Nature
2018年8月8日 · IL-2Rγ then interacts to form the high-affinity receptor 10, with signalling mediated by heterodimerization of the IL-2Rβ and IL-2Rγ cytoplasmic domains 11, 12. Interestingly, …