Interleukin 28 receptor, alpha subunit is a subunit for the interleukin-28 receptor. IL28RA is its human gene. The protein encoded by this gene belongs to the class II cytokine receptor …

Interleukin (IL) 28 receptor α (IL28RA) is a well-known candidate for psoriasis susceptibility based on previous genome-wide association study (GWAS) analysis. However, the function of …

2025年3月30日 · IFNLR1 (Interferon Lambda Receptor 1) is a Protein Coding gene. Diseases associated with IFNLR1 include Psoriasis 12 and Zika Virus Congenital Syndrome. Among its …

GWAS发现大量的银屑病易感基因，其中具有免疫功能的IL28RA基因为中国汉族人银屑病和系统性红斑狼疮的易感基因，也是欧洲人群银屑病的易感基因。 由该基因编码的蛋白质属于II类细胞 …

2025年2月8日 · Influence of Canonical and Non-Canonical IFNLR1 Isoform Expression on Interferon Lambda Signaling. Downregulated expression of IL28RA is involved in the …

IFNLR1 (interferon lambda receptor 1, also known as IL28RA) may have an essential role in anti-viral activity and immune regulation, and it has been recently reported that it inhibits human...

2024年12月20日 · Interleukin 28A (IL28A) and interleukin 28B (IL28B) may play a role in immune regulation post-AMI by specifically binding to interleukin 28 receptor alpha (IL28RA). However, …

IFN-lambda1, -lambda2, and -lambda3 bind to the same receptor (known as IL28RA) to exert their antiviral, antitumor and immunomodulatory effects. Here, we identified IL28RA genes from the …

2022年9月23日 · In our previous study, we found that downregulation of lncRNA260 could ameliorate hypoxic cardiomyocytes injury by regulating IL28RA through the activation of …

We demonstrate the protective effects of the siRNA-mediated inhibition of the interleukin-28 receptor alpha (IL28RA) subunit on cardiomyocytes in hypoxia/reoxygenation (H/R) injury and …