2011年11月1日 · iCIEF is a more suitable technique to assess charge heterogeneities of ADCs. The separation mechanism of this electrophoretic technique is based primarily on pI …

icIEF is a technique to separate proteins based on their isoelectric point. See how Maurice an automated icIEF instrument can simplify protein charge analysis.

Having been amply described already in 1960-1961, how comes that isoelectric focusing (IEF) went largely unnoticed for just about a decade? Well Harry was a free-lance scientist in a …

Experience icIEF separation and UV detection coupled with mass spectrometry identification on the ZenoTOF 7600 system. One workflow, on a single platform, enables rapid monitoring of …

2022年5月1日 · Capillary isoelectric focusing with whole-column imaging detection (icIEF) technology is now the mainstream technology to perform analytical isoelectric focusing …

2025年3月1日 · We present an integrated protocol for studying the charge heterogeneity of therapeutic proteins combining two workflows: imaged capillary isoelectric focusing (icIEF) …

2023年2月5日 · Since the first commercial imaged capillary isoelectric focusing (icIEF) instrument was developed twenty years ago, the technology has become the gold standard of quality and …

To support analysis of the charge heterogeneity of USP mAbs, we developed methods for cIEF using the SCIEX platform (PA 800 Plus) and icIEF using Bio-Techne’s Protein Simple Maurice …

2023年2月5日 · In this work, we developed a robust and flexible icIEF-MS platform which overcomes these challenges to achieve both the rapid icIEF separation and high-resolution …

Iso-electric focusing (IEF) has proven to be a very versatile separation method for the characterisation, identification, purity determination, and quantitation of amphoteric substances …