IRF7: activation, regulation, modification and function
2011年4月14日 · Interferon regulatory factor 7 (IRF7) was originally identified in the context of Epstein–Barr virus (EBV) infection, and has since emerged as the crucial...
IRF family proteins and type I interferon induction in ... - Nature
2006年2月13日 · IRF proteins also control type I IFN induction in DC. IRF-7, activated upon TLR signaling is required for IFN induction not only in pDC, but also in conventional DC (cDC) and …
文献阅读003：单细胞肿瘤浸润性髓系细胞的异质性 (综述) - 知乎
综述主要介绍了Mast、Dendritic、Monocyte、Macrophage、 Neutrophils 细胞，其中Neutrophils不是很详细，因此只总结了前4中细胞的亚群marker和特征。 以思维导图形式总结 …
IRF-7 is the master regulator of type-I interferon-dependent
2005年3月30日 · Using mice deficient in the Irf7 gene (Irf7-/- mice), we show that the transcription factor IRF-7 is essential for the induction of IFN-α/β genes via the virus-activated, MyD88 …
EMBO丨长期暴露于 TGFb1 以 IRF7 依赖性方式调节骨髓细胞炎症 …
转录因子 IRF7 是 M1 到 M2 转换所必需的，并被 TGFβ1 抑制 为了了解 TGFβ1 损害 M1 至 M2 转换的机制，作者进一步分析了全局基因表达数据，寻找表达因长期暴露于 TGFβ1 而改变的 …
干扰素调节因子 7（IRF7）基因 | MCE
This gene encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. It has been shown to play a role in the transcriptional …
IRF7: role and regulation in immunity and autoimmunity - Frontiers
2023年8月9日 · We focus on the latest regulatory mechanisms of IRF7 in IFN-I, including signaling pathways, transcription, translation, and post-translational levels, the dimerization …
IRF7 - an overview | ScienceDirect Topics
However, IRF7 is constitutively expressed in plasmacytoid DC (pDC) (also known as type I IFN-producing cells), which have the ability to rapidly produce vast amounts of type I IFN in …
IRF7: role and regulation in immunity and autoimmunity
2023年8月10日 · Interferon regulatory factor (IRF) 7 was originally identified as master transcriptional factor that produced IFN-I and regulated innate immune response, subsequent …
NCoR1 fine‐tunes type‐I IFN response in cDC1 dendritic cells by ...
2020年7月9日 · We found that NCoR1 knockdown induced a robust IFN-β-mediated antiviral response upon TLR9 activation in cDC1 DCs. At the molecular level, we showed that NCoR1 …