IRF7: activation, regulation, modification and function
2011年4月14日 · Interferon regulatory factor 7 (IRF7) was originally identified in the context of Epstein–Barr virus (EBV) infection, and has since emerged as the crucial...
Fibroblast IRF7-mediated chondrocyte apoptosis affects the …
2025年3月18日 · Irf7 mediates the fibroblast inflammatory response and affects the collapse process of SIONFH by influencing chondrocyte apoptosis. Thus, intervention in IRF7 holds …
Non-transcriptional IRF7 interacts with NF-κB to inhibit viral ...
2023年8月28日 · IRF7 interacted with the pro-inflammatory transcription factor NF-κB-p65 and inhibited the induction of inflammatory target genes. Using knockdown, knockout, and …
IRF7: role and regulation in immunity and autoimmunity
2023年8月10日 · In this review, we provide a comprehensive overview on the current knowledge of the role of IRF7 in immunity and autoimmunity. We focus on the latest regulatory …
Interferon regulatory factor 7 inhibits rat vascular smooth muscle …
2021年1月1日 · AAV-IRF7 pretreatment decreases the ATF3, PCNA, and cyclinD1 levels, coupled with increases in the levels of the Bax/Bcl2 ratio and cleaved caspase-3 in pulmonary …
Regulation of IRF7 signaling pathway in the production of IFN- I.
Interferon regulatory factor (IRF) 7 was originally identified as master transcriptional factor that produced IFN-I and regulated innate immune response, subsequent...
Serine/arginine-rich splicing factor 7 promotes the type I …
2024年3月26日 · At the Irf7 promoter, SRSF7 maximizes STAT1 transcription factor binding and RNA polymerase II elongation via cooperation with the H4K20me1 histone methyltransferase …
干扰素调节因子 7（IRF7）基因 | MCE - MCE-生物活性分子 ...
干扰素调节因子 7： 该基因编码干扰素调节因子 7，是干扰素调节转录因子 (irf) 家族的成员。它已被证明在病毒诱导细胞基因 (包括干扰素 β 链基因) 的转录激活中发挥作用。 irf7 的诱导表达 …
IRF7: role and regulation in immunity and autoimmunity - PMC
Interferon regulatory factor (IRF) 7 was originally identified as master transcriptional factor that produced IFN-I and regulated innate immune response, subsequent studies have revealed …
The multiple roles of interferon regulatory factor family in health …
2024年10月9日 · Interferon regulatory factors (IRFs) constitute a comprehensive category of transcription factors initially identified as regulators of type I interferon (IFN-I) and IFN …