Interferon regulatory factor 4 (IRF4) also known as MUM1 is a protein that in humans is encoded by the IRF4 gene. [5][6][7] IRF4 functions as a key regulatory transcription factor in the …

Mar 30, 2025 · IRF4 (Interferon Regulatory Factor 4) is a Protein Coding gene. Diseases associated with IRF4 include Skin/Hair/Eye Pigmentation, Variation In, 8 and …

Interferon Regulatory Factor 4 (IRF4) Promotes Lipopolysaccharide-Induced Colonic Mucosal Epithelial Cell Proliferation by Regulating Macrophage Polarization. A multimorphic mutation in …

We first outline the complex role of IRF4 in the function of CD4 + T cells and then discuss recent studies from our laboratory that have revealed a surprising role for components of Rho …

Nov 5, 2024 · Interferon regulatory factor 4 (IRF4) is an oncogenic transcription factor (TF) in several hematological malignancies. In multiple myeloma (MM), IRF4 serves as an MM …

What is the IRF4 gene? The interferon regulatory factor 4 ( IRF4 ) gene belongs to a family of DNA -binding proteins that play an important role in immune system development and function …

Interferon regulatory factor 4 (IRF4) is a unique IRF family member that is not regulated by interferons, instead, is mainly induced upon T-cell receptor signaling, Toll-like receptors and …

Nov 9, 2016 · IRF4 is a hematopoietic-specific transcription factor critical for lymphoid and myeloid lineage development and function, and its expression is thus restricted to immune …

Feb 19, 2025 · Title: Interferon-induced protein 44 (IFI44) and interferon regulatory factor 4 (IRF4) gene expression in rheumatoid arthritis. IRF4 impedes human CD8 T cell function and …

Genetic variants in IRF4 define the skin/hair/eye pigmentation variation locus 8 (SHEP8) [MIM:611724]. Hair, eye and skin pigmentation are among the most visible examples of …