Introduction IMC-001 is a fully human IgG1 monoclonal antibody that binds to human PD-L1 (programmed death-ligand 1). This study evaluated the safety, pharmacokinetics, and pharmacodynamics of IMC-001 in patients with advanced solid tumors.

2021年7月16日 · IMC-001 is a fully human IgG1 monoclonal antibody against PD-L1. Like other anti-PD-1/PD-L1 antibodies, it effectively enhances T cell activation and proliferation. IMC-001 maintains Fc effector function via its immunoglobulin G1 isotype Fc region to stimulate antibody-dependent cellular cytotoxicity . In our preclinical study, the anti-tumor ...

IMC- 001 blocks PD-L1 on tumor cells interacting with PD-1 on T cells, and boosts T cell activity. IMC-002 blocks CD47–SIRP-α interaction between tumor cells and macrophages and promotes tumor...

2020年5月25日 · Based on scientific rationale for neoadjuvant immunotherapy, including enhanced immune recognition, we initiated a phase II study of IMC-001, a novel PD-L1 targeting fully human monoclonal Ab in the neoadjuvant setting for resectable GC, EC, and HCC.

2020年5月26日 · imc-001是一种靶向pd-l1的全人源单克隆抗体。 本研究的目的是确定和评估 IMC-001 的有效性和安全性。 每 2 周 20mg/kg，IV 输注 IMC-001 将在患有复发性或难治性结外 NK/T 细胞淋巴瘤、鼻型的受试者中进行测试。

2023年6月15日 · 3 3 cn 113166526 a 说 明 书 1/22页 用于涂覆基材的自脱模模内涂层(imc) [0001] 本发明涉及一种组合物，其适于在模内涂覆方法中涂覆部件，涉及一种涂覆部件 的方法，并且涉及改善用于制备部件的组合物的流动行为。

imc-002是宜明昂科开发的一种cd47xcd20双靶点分子。 通过更强的ADCP活性(同时阻断CD47-SIRPα相互作用的“别吃我”信号并增强Fc-FcɣRIIa相互作用，完全激活巨噬细胞)和更强的ADCC活性(通过增强的Fc/FcɣRIIIa 相互作用来激活NK细胞)， IMC-002拥有比靶向CD20的单抗药物更强的B ...

上海长方光学仪器有限公司提供imc-1上海长方影像工具显微镜的详细技术参数信息,资料和实时价格,厂家有专业的上海长方imc-1销售和售后服务技术团队 ... (0.0001") 测角目镜分划值：6 ...

We hold micromachined tolerances as low as ±.0001″, with typical part tolerances of ±.0005″. We specialize in parts that are extremely small, and hence are able to best serve customers with part features on a scale of under .010″, and as small as .001″.

Product Code IMC 0001 [ After payment, this Code Helps to receive correct download password to your Account Dashboard] Package Include Spectrum Impco 2007-2009 LPG & BI-Fuel System 2.0L Engines Service Repair Manual