Innate lymphoid cells (ILCs) are the most recently discovered family of innate immune cells, derived from common lymphoid progenitors (CLPs). In response to pathogenic tissue damage, ILCs contribute to immunity via the secretion of signalling molecules, and the regulation of both innate and adaptive immune cells.

2022年2月28日 · The innate lymphoid cell (ILC) family is composed of natural killer (NK) cells, ILC1, ILC2 and ILC3, which participate in immune responses to virus, bacteria, parasites and transformed...

责编 | 兮 固有淋巴细胞（Innate Lymphoid Cell，简称ILC）是一类不表达特异性抗原识别受体（如T细胞受体TCR、B细胞受体BCR）的淋巴细胞。 它们的功能特点与获得性免疫系统中的T淋巴细胞相对应，并根据其表达转录因…

2018年8月23日 · Innate lymphoid cells (ILCs) are lymphocytes that do not express the type of diversified antigen receptors expressed on T cells and B cells. ILCs are largely tissue-resident cells and are deeply integrated into the fabric of tissues.

ilc主要是组织驻留细胞，可以感知周围微环境中的扰动，通过分泌细胞因子快速反应，成为协调有效免疫反应的第一响者之一。所有ilc不依赖重组活化基因（rag），由于其他免疫细胞标志物表达不足，被称为“谱系阴性”细胞。

2019年11月13日 · Innate Lymphoid Cell (ILC) 即固有淋巴样细胞是一群遍布整个机体，并在如皮肤、肺、消化道等粘膜结构富集，脂肪组织和淋巴结处也大量存在，在固有免疫调控和组织重塑中发挥重要作用的免疫细胞。ILC具备两大显著特性：

Since their discovery, innate lymphoid cells (ILCs) have been described as the innate counterpart of the T cells. Indeed, ILCs and T cells share many features including their common progenitors, transcriptional regulation, and effector cytokine ...

2020年5月6日 · Innate lymphoid cells (ILCs) are tissue-resident innate immune cells that have a similar functional diversity to T cells including lineage-specifying transcription factors...

2024年1月10日，希望之城国家医学中心余建华教授在 Cell 期刊发表了题为：Therapeutic application of human type 2 innate lymphoid cells via induction of granzyme B-mediated tumor …

2018年6月19日 · Innate lymphoid cells (ILCs) are tissue-resident correlates of T helper 1 (Th1), Th2, and Th17 cells. Colonna reviews recent advances in understanding ILC diversity and functional plasticity—their unique and redundant functions, receptor repertoires, and regulation of gene-expression programs.