
IL1R1 Gene - GeneCards | IL1R1 Protein | IL1R1 Antibody
2025年3月30日 · IL1R1 (Interleukin 1 Receptor Type 1) is a Protein Coding gene. Diseases associated with IL1R1 include Chronic Recurrent Multifocal Osteomyelitis 3 and Schnitzler …
Interleukin 1 receptor, type I - Wikipedia
Interleukin 1 receptor, type I (IL1R1) also known as CD121a (C luster of D ifferentiation 121a), is an interleukin receptor. IL1R1 also denotes its human gene. [5] The protein encoded by this …
IL-1家族信号途径及功能 - 知乎 - 知乎专栏
白细胞介素-1 (IL-1)家族细胞因子是 先天免疫系统 和 适应性免疫系统 中的关键信号分子,介导对多种刺激的炎症反应。 家族配体成员有:IL-1α、IL-1β、 IL-1Ra、 IL-18、 IL-33 、IL-36α …
IL-1家族及其各成员研究进展 - 知乎 - 知乎专栏
第一,IL-1受体拮抗剂(IL-1Ra)会与IL-1R1紧密结合,从而阻断IL-1α和IL-1β与相应受体的结合,从而阻断IL-1产生作用。 第二,IL-1R2是一种诱饵受体,具有与IL-1R1相似的细胞外区域, …
IL1R1 + cancer-associated fibroblasts drive tumor development
2023年7月17日 · Here we identify a pro-tumorigenic IL1R1 +, IL-1-high-signaling subtype of fibroblasts, using multiple colorectal cancer (CRC) patient single cell sequencing datasets. …
IL1R1- 信号通路|蛋白抗体-华美生物
il1r1,即白细胞介素-1受体1,别名cd121a、il1r、il1ra、il1rt1。 它是一种细胞膜上的受体蛋白,属于白细胞介素1(IL-1)信号通路的关键组成部分。 IL1R1来源于多种细胞类型,包括特定的 …
IL1R1 interleukin 1 receptor type 1 [ (human)] - National Center …
IL1R1 gene variants associate with disease susceptibility to IgG4-related periaortitis/periarteritis in IgG4-related disease. Expression of obesity- and type-2 diabetes-associated genes in omental …
白介素 1 受体 1 型(IL1R1)基因 | MCE - MCE-生物活性 ...
该基因编码属于白细胞介素-1 受体家族的细胞因子受体。 编码的蛋白质是白细胞介素 1 α、白细胞介素 1 β 和白细胞介素 1 受体拮抗剂的受体。 它是参与许多细胞因子诱导的免疫和炎症反应 …
Molecular mechanisms of regulation of IL-1 and its receptors
2024年10月5日 · Genetics of the IL-1 receptor (IL1R1) in epithelial cells facilitated oncogenesis in a colorectal cancer model, demonstrating a cell-autonomous role of IL-1 signalling in early …
Cell-Type-Specific Interleukin 1Receptor 1 Signaling in the …
We used a genetic knockin reporter system in mice to track and reciprocally delete or express IL-1 receptor 1 (IL-1R1) in specific cell types, including endothelial cells, ventricular cells, …