
IL21R Gene - GeneCards | IL21R Protein | IL21R Antibody
2025年3月30日 · IL21R (Interleukin 21 Receptor) is a Protein Coding gene. Diseases associated with IL21R include Immunodeficiency 56 and Cryptosporidiosis-Chronic Cholangitis-Liver …
肿瘤治疗多效细胞因子——IL21 - 知乎
取野生型小鼠和纯合B-hIL21R小鼠的脾细胞,用种属特异性的抗IL21R抗体进行流式细胞术分析。 在野生型小鼠中检测到鼠IL21R的表达;在纯合B-hIL21R小鼠中只检测到人IL21R的表达,不 …
IL-21:多效到惊呼厉害的细胞因子 - 知乎
IL-21受体(IL-21R)是一个由独有的亚单位和γ链组成的异二聚体,在淋巴细胞和造血细胞表面广泛表达。 γ链可与IL-2、 IL-4 、 IL-7 、 IL-9 和IL-15等细胞因子结合。
我是两面派,↓ B 细胞,↑T 细胞——IL21 - 丁香通
2017年9月1日 · 在 CD4+和 CD8+ T 细胞亚群, 都可检测到 IL-21R 的表达。 IL-21 可增强各类由抗 CD3 诱导的 T 细胞增殖, 包括鼠胸腺细胞和浓缩的外周 T 细胞、人类幼稚 T 细胞,IL-21 可增强 …
Interleukin-21 receptor - Wikipedia
Interleukin 21 receptor is a type I cytokine receptor. IL21R is its human gene. [5] The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21).
Biology of IL-21 and the IL-21 receptor - PubMed
Its private receptor, IL-21R, has been shown to activate the Janus kinase/signal transducers and activators of transcription signaling pathway upon ligand binding. Initial studies have …
IL-21R functions as an oncogenic factor and is regulated by
Interleukin-21 receptor (IL-21R) is involved in the immunological regulation of immune cells and tumor progression in multiple malignancies. However, the potential molecular mechanisms …
Interleukin 21 - Wikipedia
The IL-21 receptor (IL-21R) is expressed on the surface of T, B and NK cells. IL-21r is similar in structure to the receptors for other type I cytokines like IL-2R [15] or IL-15 and requires …
IL-21 Signaling in Immunity - PMC
IL-21 is a type I cytokine produced by T cells and natural killer T cells that has pleiotropic actions on a wide range of immune and non-immune cell types. Since its discovery in 2000, extensive …
IL21R interleukin 21 receptor [Homo sapiens (human)] - Gene
2024年12月9日 · The IL21/IL21R axis reduced the growth and invasion of NSCLC cells via inhibiting Wnt/betacatenin signaling and PDL1 expression. The present results may provide a …