
Interferon type I - Wikipedia
Interferon Type I (α/β/δ...) The molecular structure of human interferon-beta (PDB: 1AU1 ). The type-I interferons (IFN) are cytokines which play essential roles in inflammation, …
Ⅰ型干扰素(IFN)家族及其生物学功能概述 - 知乎
II型IFN家族由单一基因产物 IFNγ 组成,主要由T细胞和自然杀伤(NK)细胞产生,能作用于表达IFNγ受体(IFNγR)的细胞类型。 III型IFN家族包括 IFNλ1 、 IFNλ2 和 IFNλ3 (也分别称为IL …
干扰素IFN家族成员 - 知乎 - 知乎专栏
20世纪50年代首次发现 I型干扰素,1965年首次发现 II型干扰素,2003年,两个研究组分别报告发现了三种新的干扰素样细胞因子,分别称为 IFNλ1 、λ2和λ3或 白细胞介素-29 (IL-29)、IL …
Type I interferons in infectious disease - Nature
2015年1月23日 · Type I interferons (IFNs) have diverse effects on innate and adaptive immune cells during infection with viruses, bacteria, parasites and fungi, directly and/or...
Ⅰ型干扰素:不仅是抗病毒细胞因子更是免疫系统的“超能力者”
干扰素IFNs是广泛表达的细胞因子,是机体受到病毒侵染时产生的具有多方面抗病毒和细胞免疫调节功能的关键因子。 IFN家族可分为三种主要类型:I型、II型和III型。 I型干扰素不仅是抗病毒 …
The Type I Interferons: Basic Concepts and Clinical Relevance in …
Type I IFNs elicit antiviral, antiproliferative and immunomodulatory responses by binding to the type I interferon receptor. The receptor consists of the IFNAR1 and IFNAR2 transmembrane …
IFNA1 Gene - GeneCards | IFNA1 Protein | IFNA1 Antibody
2025年3月30日 · IFNA1 (Interferon Alpha 1) is a Protein Coding gene. Diseases associated with IFNA1 include Hepatitis and Newcastle Disease . Among its related pathways are Overview of …
Regulation of type I interferon responses - Nature
2013年12月23日 · Type I interferon (IFN) responses are regulated by host, pathogen and environmental factors. These factors calibrate the host defences while limiting tissue damage …
Type 1 interferons: A target for immune-mediated ... - ScienceDirect
2024年3月1日 · Interferons (IFNs) type I, particularly IFN-α, are central mediators in the pathogenesis of several Immune-mediated inflammatory diseases (IMIDs). IFN-blocking …
The crucial regulatory role of type I interferon in inflammatory ...
2023年12月20日 · Type I interferon (IFN-I) plays crucial roles in the regulation of inflammation and it is associated with various inflammatory diseases including systemic lupus …
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