The I region of the mouse H-2 gene complex codes for four Ia genes, Aα, Aβ, Eβ and Eα, whose gene products express the Ia determinants. Aα, Aβ and Eβ map within the I-A subregion, while …

Interspecies cross-reactions of anti-Ia mouse alloantibodies have indeed been observed. Although such a cross-reaction was first found between mouse I–A and rat Ia-homologues, subsequent...

1986年1月1日 · Expression of the murine Ia antigens is highly regulated, normally being limited to only a few cell types. Much of the regulation takes place at the level of mRNA synthesis; how …

The contributions of different allelically variable regions of Ia molecules to both of these processes were analyzed by transfection of L cells with various A beta and A alpha gene pairs. The …

The human gene encoding the Ia-associated gamma (or invariant) chain was isolated by screening a genomic library in phage lambda with cDNA probes. The frequency of positive …

The Ia antigens constitute a polymorphic series of cell surface determinants. At present, their definition is mainly a genetic one, and thus any cell surface antigen which can be …

The class II genes code for the classical ‘Ia antigens’ which consists of two polypeptide chains of 31,000 and 28,000 daltons in a non-covalent association and expressed predominantly on …

Ia alloantigens are surface glycoproteins found on lymphocytes and macrophages and probably some other cell types (Shreffler and David, 1975; Hammerling et al., 1975; Cowing et al., …

2004年5月12日 · Phospholipase A 2 (PLA 2) genes expressed in the venom glands of the sea snake, Laticauda semifasciata, were investigated. Both mRNAs, encoding group IA (without a …

Gene rearrangement of adaptive immune antigen recognition receptors proceeds in individual lymphocytes (Eason et al., 2004; Imkeller & Wardemann, 2018; Yanagi et al., 1985). The …