In this study, a liquid formulation of platelet rich fibrin (PRF) termed injectable-PRF (i-PRF) without the use of anti-coagulants was investigated. Materials and methods: Standard PRP and i-PRF (centrifuged at 700 rpm (60G) for 3 min) were compared for growth factor release up to 10 days (8 donor samples).

2024年11月29日 · Regular PRF, following centrifugation, reveals a 3-dimensional fibrin matrix, rendering it unsuitable for use as an injection. As a result, injectable PRF (I-PRF), a liquid counterpart of PRF, that makes no use of anticoagulants, was proposed as a result of pioneering development of the low-speed centrifugation concept.

2022年3月1日 · In this review, in-vitro, in-vivo and clinical performance of I-PRF have been reviewed. Based on the method of harvesting I-PRF, two types of I-PRF have been introduced: yellow and red I-PRF. To optimize I-PRF for long-term …

PRF ® PROCESS system technology was used to prepare i-PRP. Eleven healthy female individuals were included in the study and over 3-months received monthly intradermal injections of i-PRF in 3 facial regions: malar areas (1 mL each side), nasolabial fold (0.5 mL each side), and upper lip skin above the vermilion border (1 mL).

2023年11月5日 · PRP （Platelet-Rich Plasma，富血小板血浆） 它是在1984年 Assoian 等报道的第一代自体富血小板血液制品，它的准备方法是通过向全血中添加抗凝剂，如氯化钙、凝血酶等化学物再通过离心从全血中分离出的高浓度血小板血浆。 由于富血小板血浆的制作和临床效果因需加入抗凝剂以及离心效果差而备受争议。 PRF （Platelet-RichFibrin，富血小板纤维蛋白） 它是 2000年报道的第二代富血小板血液制品，它的制备方法是通过全血不添加任何抗凝剂立刻一 …

However, recent research provided new protocol for liquid variation of PRF called injectable PRF (i-PRF). This injectable form of PRF is produced by using blood without anticoagulant and centrifuged at 700 rpm (60 g) for 3 min in plastic tubes without any coatings [46].

Injectable platelet-rich fibrin (I-PRF) is a second generation, fully autologous, blood-derived biomaterial having three-dimensional fibrin meshwork, like that of a PRF clot, while retaining the fluid nature, just like platelet-rich plasma (PRP).

Modifications to centrifugation protocols and tube technology have led to the development of a liquid injectable version of PRF (i-PRF). This narrative review takes a look back at the technological developments made throughout the past decade and further elaborates on their future clinical applications.

2020年9月29日 · Injectable platelet-rich fibrin (I-PRF) is a second generation, fully autologous, blood-derived biomaterial having three-dimensional fibrin meshwork, like that of a PRF clot, while retaining the fluid nature, just like platelet-rich plasma (PRP).

2022年11月1日 · In 2014, by adjusting spin centrifugation forces, injectable platelet-rich fibrin (I-PRF) was developed. The blood centrifuged in non-glass centrifugation tubes at lower centrifugation speeds resulted in a flowable PRF called I-PRF [10].