
Comprehensive review on the HSC70 functions, interactions with …
2019年10月3日 · Heat shock cognate protein 70 (HSC70) is a constitutively expressed molecular chaperone which belongs to the heat shock protein 70 (HSP70) family. HSC70 shares some of …
HSPA8 - Wikipedia
Heat shock 70 kDa protein 8 also known as heat shock cognate 71 kDa protein or Hsc70 or Hsp73 is a heat shock protein that in humans is encoded by the HSPA8 gene on chromosome …
热激蛋白70 - 百度百科
热激蛋白70又称 热休克蛋白 70(heatshockprotein70,HSP70)是一种结构上高度保守的多肽,能够通过易化变性蛋白的修复,帮助新合成的多肽键的生理折叠与伸展,以及纠正多肽链的错误 …
其表达,因此,热休克蛋白又被称为应激蛋白。作为进化上最保守的蛋白质之一,热休克蛋白70 (heat shock protein 70, Hsp70)是生物细胞中含量最高的一种热休克蛋白,可诱导性最强,具有多�. 生 …
Hsc70 promotes anti-tumor immunity by targeting PD-L1 for
2024年5月18日 · Our findings revealed that Hsc70 overexpression (Hsc70-OE) or PD-L1 knockdown (PD-L1-KD) effectively suppressed tumor growth, while the combination of both …
Similarities and Differences of Hsp70, hsc70, Grp78 and …
Hsc70 has been studied most extensively in glioma where its regulation of proliferation and apoptosis was shown to involve binding and regulation of β4-galactosyltransferase 5 . Overall, …
IF14.3! 中科院1区!Mfn2/Hsc70介导的线粒体-脂滴相互作用在心 …
研究团队利用高脂饮食(HFD)诱导的肥胖小鼠模型和原代培养的心肌细胞,通过Mfn2的过表达和敲除、免疫共沉淀、免疫荧光等实验,研究了Mfn2与Hsc70在MLC形成中的相互作用
Hsc70 - a chaperone protein with diverse cellular functions
2015年5月15日 · Hsc70, with the help of accessory proteins, exerts its chaperone activity by binding to short hydrophobic stretches of nascent or unfolded polypeptides through the SBD in …
浙江大学医学院研究者们揭示了Hsc70通过靶向PD-L1溶酶体降解 …
该研究阐明了hsc70介导的PD-L1溶酶体降解的分子机制,为未来癌症免疫治疗的发展提供了途径。 Hsc70通过eMI靶向PD-L1降解促进抗肿瘤免疫的示意图模型
人类 71 kDa 热休克同源蛋白 (HSPA8/hHsc70) 的结构、热力学和功 …
人类 71 kDa 热休克同源蛋白(HSPA8,也称为 Hsc70、Hsp70-8、Hsc71、Hsp71 或 Hsp73)是组成型表达的分子伴侣,对细胞蛋白质稳态至关重要。 在胞质溶胶中,HSPA8 在折叠和重折 …