
HOX gene expression in the developing human spine - Nature
2024年11月20日 · We analyse HOX gene expression across cell types during development, finding that neural-crest derivatives unexpectedly retain the anatomical HOX code of their …
Establishing and maintaining Hox profiles during spinal cord ...
2024年1月1日 · This review outlines the mechanisms of Hox gene regulation during spinal cord development, focusing on the process of MN subtype differentiation. We will categorize these …
HOX gene expression in the developing human spine - PubMed
2024年11月20日 · In the axial plane of the spinal cord, we find distinct patterns in the ventral and dorsal domains, providing insights into motor pool organisation and loss of collinearity in …
Hox genes and spinal cord development - PubMed
Hox genes encode homeodomain-containing proteins with overlapping rostrocaudal domains of expression in the developing spinal cord. Rostrally expressed Ant-p/Ubx/Abd-D-related Hox …
Expression of Hox Genes in the Nervous System of Vertebrates
Hox gene expression in the 12.5 dpc anterior-posterior (A-P) axis of the mouse spinal column. Hox genes from groups 5 to 13 begin their expression in the spinal column. Since the spinal …
Hox Genes: Choreographers in Neural Development, Architects …
A common theme from studies of Hox specificity in the hindbrain and spinal cord is the regulation of both converging and diverging pathways by Hox proteins. Several Hox functions appear to …
Establishing and maintaining Hox profiles during spinal cord ...
The chromosomally-arrayed Hox gene family plays central roles in embryonic patterning and the specification of cell identities throughout the animal kingdom. In vertebrates, the relatively …
A Hox Code Defines Spinocerebellar Neuron Subtype …
2019年11月19日 · Using fluorescent reporter mice, neuronal tracing, and in situ hybridization, we identify widespread expression of Hox cluster genes within spinocerebellar neurons. We …
(PDF) HOX gene expression in the developing human spine
2024年11月20日 · We analyse HOX gene expression across cell types during development, finding that neural-crest derivatives unexpectedly retain the anatomical HOX code of their …
Deterministic HOX Patterning in Human Pluripotent Stem Cell …
The discovery that Wnt/FGF signaling induces NMPs that progressively caudalize HOX expression and undergo RA-induced neuroectoderm differentiation to form the hindbrain and …