Homology directed repair - Wikipedia
Homology-directed repair (HDR) is a mechanism in cells to repair double-strand DNA lesions. [1] The most common form of HDR is homologous recombination . The HDR mechanism can only …
CRISPR 101: Homology Directed Repair - Addgene
In this post, we will describe the mechanism of homology directed repair, one of the repair pathways of DSBs, with a focus on repair for genome modification purposes. How does …
Homology Directed Repair - an overview | ScienceDirect Topics
The reparation process may be performed in two different ways, homology-directed repair (HDR) and non-homologous end-joining (NHEJ), both of which can be used to acquire the desired …
CRISPR-Cas9-mediated homology-directed repair for precise ...
2024年12月10日 · CRISPR-Cas9-mediated homology-directed repair (HDR) is a versatile platform for creating precise site-specific DNA insertions, deletions, and substitutions. These …
Efficient high-precision homology-directed repair-dependent ...
2023年7月20日 · Homology-directed repair (HDR), a method for repair of DNA double-stranded breaks can be leveraged for the precise introduction of mutations supplied by synthetic DNA …
Homology Directed Repair CRISPR: Key Advances and Methods
2025年3月24日 · Homology-directed repair (HDR) is a key pathway that facilitates accurate gene correction using homologous DNA templates. This method holds promise for treating genetic …
On the Origins of Homology Directed Repair in Mammalian Cells
The foundation of homology directed repair lies in pioneering work that unravel the mystery surrounding genetic exchange using single-stranded DNA oligonucleotides as the sole gene …