Homologous recombination is a type of genetic recombination in which genetic information is exchanged between two similar or identical molecules of double-stranded or single-stranded nucleic acids (usually DNA as in cellular organisms but may be also RNA in viruses).

Diagram the process of homologous recombination to explain how meiosis generates new combinations of alleles on chromosomes. Understand that recombination involves a physical breakage and ligation of the DNA backbones of sister chromatids and occurs during the pachytene of prophase of meiosis I.

4 天之前 · Homologous recombination is a type of genetic recombination in which nucleotide sequences are exchanged between two similar or identical molecules of DNA.

Homologous recombination, the exchange of genetic material between two strands of DNA that contain long stretches of similar base sequences. Homologous recombination occurs naturally in eukaryotic organisms, bacteria, and certain viruses and is a powerful tool in genetic engineering.

2008年1月1日 · Homologous recombination (HR) is a DNA metabolic process found in all forms of life that provides high-fidelity, template-dependent repair or tolerance of complex DNA damages including DNA...

The central protein involved in homologous recombination is RecA, which promotes the exchange of strands between homologous DNAs that causes heteroduplexes to form (Figure 5.35). The action of RecA can be considered in three stages.

Homologous recombination (HR) is the process of repairing DNA lesions using homologous DNA sequences. It is a prominent feature of meiosis that allows homologous chromosomes to pair up and faithfully segregate into haploid gametes.

In essence, homologous recombination is the guardian of the genome, where mutations in genes encoding recombination functions can lead to the development of cancer (e.g., BRCA1) or to instability of chromosomal structures and numbers.

Homologous recombination is the most complex of all recombination events that shape genomes and produce material for evolution. Homologous recombination events are exchanges between DNA molecules in the lengthy regions of shared identity, …

Homologous recombination (HR) is a fundamental process common to all species. HR aims to faithfully repair DNA double strand breaks. HR involves the formation of nucleoprotein filaments on DNA single strands (ssDNA) resected from the break.