Type I Toxin-Antitoxin Loci: hok/sok and fst | SpringerLink
2012年10月19日 · The unraveling of the mechanism of plasmid stabilization yielded a surprise: hok / sok increases plasmid maintenance by killing of plasmid-free cells, a mechanism known …
Profiling the intragenic toxicity determinants of toxin–antitoxin ...
We revealed the death-inducing phenotype of the Hok toxin when it is expressed from the chromosome in the absence of the antitoxin and recovered previously described intragenic …
质粒中遗传毒素-抗毒素元件 hok/sok 的位置和方向影响细菌细胞 …
在这项工作中，我们研究了具有诱导型 T7lac启动子和卡那霉素抗性基因的标准pET28a质粒中hok / sok 元件的位置和方向的影响。 研究发现，无论 hok / sok 元件在质粒中的位置和方向如何，它 …
Mechanism of post-segregational killing by the hok/sok system of ...
1992年1月5日 · Hok mRNA encodes the Hok killer protein of 52 amino acid residues. Expression of hok is regulated post-transcriptionally by Sok antisense RNA.
The role of the hok/sok locus in bacterial response to stressful …
2015年2月1日 · The hok / sok locus is a well established type 2 toxin/antitoxin system which was originally discovered due to its stabilizing activity on the inheritance of plasmid R1 [1]. It …
Mechanism of post-segregational killing by the hok/sok system …
1992年1月5日 · The hok/sok locus of plasmid R1, which mediates plasmid stabilization by killing of plasmid-free segregants, codes for two RNAs, Hok mRNA and Sok antisense RNA. Hok …
The role of the hok/sok locus in bacterial response to ... - PubMed
The hok/sok locus is renowned for its plasmid stabilization effect via post-segregational killing of plasmid-free daughter cells. However, the function (s) of the chromosome-encoded loci, which …
Mechanism of post-segregational killing by the hok/sok system of ...
质粒R1的hok / sok基因座通过杀死无质粒的分离子介导质粒的稳定，编码两个RNA，即Hok mRNA和Sok反义RNA。 Hok mRNA编码52个氨基酸残基的Hok杀手蛋白。 hok的表达受Sok …
Location and Orientation of the Genetic Toxin–Antitoxin Element
In this work, we studied the effects of position and orientation of the hok / sok element in the standard pET28a plasmid with the inducible T7lac promoter and kanamycin resistance gene. It …
一种含hok/sok基因的菌株及其制备与应用 - X技术网
2024年5月9日 · 迄今为止，hok/sok基因的研究多集中在探究其机制及其在合成生物学中的应用，但关于运用于提升蛋白水平的质粒稳定性系统鲜有报道，且hok/sok基因的插入位点的选择 …