Structural basis for thioredoxin-mediated suppression of NLRP1
2023年9月13日 · Human NLRP1 (NLRP1) is a multi-domain protein that comprises an N-terminal pyrin domain (PYD), a disordered linker region, a central NOD, a leucine-rich repeat (LRR) …
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Structural and biochemical mechanisms of NLRP1 inhibition …
2021年4月29日 · Structure-guided biochemical and functional assays show that both NLRP1 binding and enzymatic activity are required for DPP9 to suppress NLRP1 in human cells. …
Issue #426 · yuaotian/go-cursor-help - GitHub
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Emerging insights into molecular mechanisms underlying pyroptosis and ...
2019年10月17日 · Two pathways have been found to trigger pyroptosis: caspase‐1 mediated inflammasome pathway with the involvement of NLRP1‐, NLRP3‐, NLRC4‐, AIM2‐, …
NLRP3 is a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. It interacts with the apoptosis-associated speck-like …
(PDF) EEF2-inactivating toxins engage the NLRP1 ... - ResearchGate
2023年1月17日 · Here, together with a companion study, we report that the NLRP1 inflammasome detects Exotoxin A (EXOA), a ribotoxin released by P. aeruginosa Type 2 …
(2E)-2-(4-ethoxybenzylidene)-3,4-dihydro-2H-naphthalen
2021年11月15日 · In this present investigation, a new α-Tetralone based chalcone compound, (2E)-2- (4-ethoxybenzylidene)-3,4-dihydro-2H-naphthalen-1-one (EBDN) has been …
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