2014年4月20日 · Cross-linked CLC-ec1 adopts a wild-type–like structure, indicating stabilization of a native conformation. Movements of helix O are transduced to the ion pathway via a direct …

2004年2月6日 · The polymerase active site regions of DNA polymerase I and T7 RNAP are particularly similar, including two homologus aspartic acid residues that bind two catalytic …

We found that the mutations on ClC-1 helix O caused the current smaller than that of myotonia mutations on other helixes. We also found that the helix O mutations on ClC-2 reduced the …

In this study, we characterized highly conserved helix O as a key determinant of structural stability in CLC-1. Supporting this hypothesis, myotonic mutant (G523D) at N-terminal of helix O …

A helix (/ ˈ h iː l ɪ k s /; pl. helices) is a shape like a cylindrical coil spring or the thread of a machine screw. It is a type of smooth space curve with tangent lines at a constant angle to a …

α-螺旋（α-helix）是蛋白质二级结构的主要形式之一。 指多肽链主链围绕中心轴呈有规律的螺旋式上升，每3.6 个氨基酸残基螺旋上升一圈，向上平移0.54nm，故螺距为0.54nm，两个氨基酸 …

2017年2月1日 · In this study, we characterized highly conserved helix O as a key determinant of structural stability in CLC-1. Supporting this hypothesis, myotonic mutant (G523D) at N …

2014年12月4日 · From close examination of the closed crystal structure, an arginine and lysine in the O-helix form salt bridges to help neutralize the negative charge of the triphosphate on the …

An α-helix is a right-handed coil of amino-acid residues on a polypeptide chain, typically ranging between 4 and 40 residues. This coil is held together by hydrogen bonds between the oxygen …

2024年1月27日 · 首先 10x 选择十行，第二步 s 命令搜索 helix，第三步 c 命令替换选择的单词为Helix，最后「,」结束选择。 而 VIM 则可以使用多行正则表达式搜索命令： …