2024年11月20日 · Harvoni is used to treat hepatitis C virus (HCV) infections in adults and children aged 3 years and older. Harvoni treats HCV genotypes 1, 4, 5, or 6 infections without cirrhosis or with compensated cirrhosis; HCV genotype 1 infection with advanced cirrho

HARVONI is a prescription medicine used to treat adults with chronic (lasting a long time) hepatitis C (Hep C) genotype (GT) 1, 4, 5 or 6 infection with or without cirrhosis (compensated).

Ledipasvir/sofosbuvir, sold under the trade name Harvoni among others, is a medication used to treat hepatitis C. [8] It is a fixed-dose combination of ledipasvir and sofosbuvir. [8] Cure rates are 94% to 99% in people infected with hepatitis C virus (HCV) genotype 1. [9] Some evidence also supports use in HCV genotype 3 and 4. [9]

2018年5月21日 · 联合利巴韦林 治疗失代偿期肝硬化的基因1型成人慢性丙肝患者。 【作用机制】 主要成分索磷布韦（索非布韦）是NS5B聚合酶抑制剂，是一种丙型肝炎病毒（HCV）聚合酶抑制剂，作用于病毒RNA复制的核苷酸类似物NS5B聚合酶位点，能中止病毒复制。 【不良反应】 疲劳、头痛、恶心与失眠。 【治疗】固定剂量复合药：雷迪帕韦（ledipasvir）90mg与索磷布韦（索非布韦）400mg。 用于治疗1、6型成年慢性丙肝患者。 具体为：（包括17年FDA新增适应症） …

2014年10月11日 · 10月10日，美国FDA批准Harvoni（Ledipasvir和Sofosbuvir)用于治疗慢性丙型肝炎毒 (HCV)基因型1感染。 Harvoni是首款获批用于治疗慢性HCV基因型1感染的复方药物。 它也是首个获批的不需要干扰素或利巴韦林的治疗方案，干扰素和利巴韦林也是FDA批准的用于治疗慢性HCV感染的药物。 Harvoni中的两款药物可干扰HCV增殖所需要的酶。 Sofosbuvir是一款之前被批准的HCV药物，以Sovaldi为商品名上市销售。 Harvoni中还包含了一款新的药物Ledipasvir …

HARVONI is indicated for the treatment of adults and pediatric patients 3 years of age and older with chronic hepatitis C virus (HCV) genotype (GT) 1, 4, 5, or 6 infection without cirrhosis or with compensated cirrhosis. HARVONI is used with ribavirin in GT 1 patients with decompensated cirrhosis and in GT 1 or 4 liver

Harvoni is an antiviral medicine used to treat adults and children from 3 years of age with chronic (long-term) hepatitis C, an infectious disease of the liver caused by the hepatitis C virus. Harvoni contains the active substances ledipasvir and sofosbuvir.

2025年3月6日 · Overview: Ledipasvir/sofosbuvir is used to treat chronic hepatitis C virus (HCV) infection. It works by preventing the hepatitis C virus from making copies of itself. Common side effects include...

2024年8月23日 · Ledipasvir-sofosbuvir (Harvoni) is one of the most effective treatments for hepatitis C. Learn about how the drug works, who can take it, its risks, side effects, cost, and more.

2021年6月25日 · HARVONI is a fixed-dose combination of ledipasvir, a hepatitis C virus (HCV) NS5A inhibitor, and sofosbuvir, an HCV nucleotide analog NS5B polymerase inhibitor, and is indicated for the treatment of chronic hepatitis C virus (HCV) in: Adults with genotype 1, 4, 5, or 6 infection without cirrhosis or with compensated cirrhosis