5-HT4-受体 西沙必利(Cisapride)为一种上胃肠道蠕动促进剂。 用于胃轻瘫：上消化道不适、胃－食管反流、与运动功能失调有关的假性肠梗阻、慢性便秘病人的长期治疗。

5-HT综合征 属于精神科急症，主要临床表现包括5-HT受体过度激活引起的自主神经功能亢进如心跳加速和呼吸加快、神经肌肉功能紊乱如肌肉无意识抖动痉挛，及精神状态改变如焦虑不安 …

5-Hydroxytryptamine receptor 4 is a protein that in humans is encoded by the HTR4 gene. [5][6] This gene is a member of the family of human serotonin receptors, which are G protein …

5-HT4 receptors are a type of serotonin receptors that play a key role in controlling brain functions such as learning, memory, mood, and gastrointestinal transit. They are a target for therapeutic …

2020年2月10日 · 5-HT4 受体激动药可作用于胃肠道胆碱能中间神经元及肠肌间神经丛的 5-HT4 受体，使兴奋性神经元释放乙酰胆碱增加，增强食道、胃、十二指肠及小肠的协调运动，促进消 …

5-HT4受體 或 5-羥色胺受體4 （英語： 5-Hydroxytryptamine receptor 4）是在人類上由 HTR4 基因 編碼的蛋白質 [6][7]。 ^ 對5-hydroxytryptamine receptor 4起作用的藥物；在維基數據上查 …

2024年5月11日 · In recent years, particular attention has been paid to the serotonin 4 receptor, which is well expressed in the brain, but also peripherally in various organs. The cerebral …

预测该基因编码的蛋白编码的蛋白可启动 G 蛋白偶联血清素受体活性；神经递质受体活性；和血清素结合活性。 预计参与G蛋白偶联受体信号通路；化学突触传递；和γ-氨基丁酸信号通路。 预 …

2020年4月3日 · Animal experimental studies suggest that 5-HT 4 receptor activation holds promise as a novel target for the treatment of depression and cognitive impairment. 5-HT 4 …

2014年8月21日 · Over the past decade, the 5-HT4 receptor has been highlighted as an attractive drug target for the treatment of gastrointestinal motility disorders such as irritable bowel …