Determination of human papillomavirus type in archival tissue
2022年4月5日 · In our previous study, an L1-based human papillomavirus (HPV) test using liquid-based cytology revealed that some invasive cervical cancers (ICC) exhibited multiple HPV types or harbored no HPV DNA. Here, molecular mapping of formalin-fixed paraffin-embedded cancer tissue specimens from the same patients were conducted to confirm these ...
HPV L1 detection discriminates cervical precancer from transient HPV ...
2013年2月15日 · This study shows that HPV-L1 capsid protein analysis with Cytoactiv is able to predict the clinical outcome of early dysplastic lesions, helps to discriminate transient HPV infection from HPV...
HPV genotyping by L1 amplicon sequencing of archived invasive …
2022年8月9日 · We used high-throughput sequencing of a single amplicon within the HPV L1 gene to assess the influence of patient age, race/ethnicity, histological subtype, sample type, collection date, experimental factors, and computational parameters on the prevalence of HPV genotypes detected in archived DNA (n = 34), frozen tissue (n = 44), and formalin ...
HPV L1 C-末端保守序列多肽免疫学特性的探讨-期刊-万方数据知 …
2014年2月18日 · 摘要： 目的：探讨一段位于人乳头状瘤病毒（hpv）l1c-末端、长30个氨基酸残基的保守序列的免疫学性质而进行此实验。方法以此序列为基础人工合成多肽加氢氧化铝佐剂免疫小鼠。
In silico/In vivo analysis of high-risk papillomavirus L1 and L2 ...
2019年10月23日 · In this study, we developed DNA constructs (based on L1 and L2 genes) that were potentially immunogenic and highly conserved among the high-risk HPV types.
High-Risk HPV Oncoproteins and PD-1/PD-L1 Interplay in Human …
This review aims to underline the interrelation between high-risk HPV oncoproteins and PD-1/PD-L1 in the pathogenesis of cervical cancer, which could reinforce the role of PD-1/PD-L1 inhibitors as one of the main therapies for the management of …
HPVL1多肽抗体检测HPV感染能力及确证多肽抗血清中和HPV16能 …
本课题组前期的研究结果表明:由课题组发现并已成功申请专利的人乳头瘤病毒(hpv)主要衣壳蛋白l1c-末端共同保守序列多肽,能够诱导动物产生的抗血清,对多种型别hpvl1具有交叉的免疫反应性,并且对多种hpv型别具有检测能力和一定的中和hpv病毒能力。
HPV L1/PD-L1检测联合阴道镜检查在宫颈癌前病变及宫颈癌中的临 …
Objective To explore the expression of human papilloma virus (HPV) L1 protein and programmed cell death ligand-1 (PD-L1) protein in cervical precancerous lesions and cervical cancer, to analyze...
HPV L1 C-末端保守序列多肽免疫学特性的探讨.pdf
hpv l1 c-末端保守序列多肽免疫学特性的探讨.pdf,12 重庆医学2014年 1月第 43卷第 1期 · 论 hpvl1c一末端保守序列多肽免疫学特性的探讨 蒋雪梅 ，肖长义 ，昊江峰，李红军 ，袁太宁，汤桂成 (三峡大学医学院，湖北宜昌443002) 摘 要：目的 探讨一段位于人乳头状瘤病毒(hpv)l1c一
HPV L1C-末端保守序列多肽免疫学特性的探讨 - 道客巴巴
·论 著·HPV L1C－末端保守序列多肽免疫学特性的探讨＊蒋雪梅，肖长义 ，吴江峰，李红军，袁太宁，汤桂成（三峡大学医学院，湖北宜昌443002） 摘 要：目的 探讨一段位于人乳头状瘤病毒（HPV）L1C－末端、长30个氨基酸残基的保守序列的免疫学性质而进行此实验。