Effect of HLA mismatch on acute graft-versus-host disease
HLA matching between donors and recipients is the most important factor associated with acute graft-versus-host disease (GVHD) following allogeneic hematopoietic stem cell …
异基因造血干细胞移植急性移植物抗宿主病诊断与治疗中国专家共 …
在hla不合非血缘供者移植中，与钙调磷酸酶抑制剂+mtx相比，加用阿巴西普的三药联合可明显降低Ⅲ/Ⅴ度急性gvhd的发生率（2.3%）；钙调磷酸酶抑制剂+mtx联合阿巴西普组与钙调磷酸酶 …
High HLA-DP Expression and Graft-versus-Host Disease
2015年8月13日 · Transplantation of hematopoietic cells from unrelated donors can cure blood disorders but carries a significant risk of acute graft-versus-host disease (GVHD). The risk is …
Role of HLA-DP Expression in Graft-Versus-Host Disease After …
2020年6月1日 · To ascertain the role of HLA-DPB1 expression on acute GVHD risk in HLA-9/10 transplantation, we examined GVHD risks associated with one high-expression compared with …
Individual HLA alleles and risk of graft-versus-host disease after ...
2020年5月25日 · Graft-versus-host disease (GVHD) in its acute (aGVHD) and chronic (cGVHD) form remains one of the most serious complications of allogeneic haematopoietic stem cell …
Current approaches to prevent and treat GVHD after allogeneic stem …
2018年11月30日 · Graft-versus-host disease (GVHD) remains a challenge after allogeneic hematopoietic cell transplantation (HCT). GVHD occurs when immunocompetent donor T cells …
Systematic mining and quantification reveal the dominant ... - Nature
2025年3月4日 · Human leukocyte antigen (HLA) disparity between donors and recipients is a key determinant triggering intense alloreactivity, leading to a lethal complication, namely,...
【Nature子刊】综述：急性移植物抗宿主病 - MedSci
2024年8月28日 · 急性GVHD是由供体免疫效应细胞对受体组织和器官的识别和破坏所引起，通常发生于alloHCT后的前3个月内，但也可能迟发。急性GVHD的靶器官包括皮肤、消化道和肝 …
Optimizing stem cell infusion timing in the prevention of acute …
5 天之前 · A primary challenge in allogeneic hematopoietic stem cell transplantation (allo-HSCT) is graft-versus-host disease (GVHD), ... HLA typing of donors and patients was performed via …
Cutaneous Manifestations of Graft Versus Host Disease (GvHD)
2025年3月28日 · The pathophysiology, risk factors, and prognostic implications of GvHD are detailed, including the impact of donor-recipient HLA disparity and transplant conditioning …