2023年3月21日 · H3K27me3 is reported to rarely be lost in a subset of other tumors, such as meningioma, radiation associated unclassified sarcoma, radiation associated angiosarcoma, …

2022年4月14日 · H3K27me3: H3 K27-altered tumors show loss of H3K27me3 staining, a finding that by itself is not specific, however, may be helpful in identifying diffuse midline gliomas with …

2023年10月31日 · Loss of H3K27 trimethylation (H3K27me3) by IHC predicts poor prognosis in grade 1 and 2 meningiomas but not grade 3 (Acta Neuropathol 2018;135:955) TERT promoter …

2021年9月13日 · Also can have loss of H3K27me3 in 34% of cases (Mod Pathol 2016;29:582) Cellular schwannoma: Dilated vessels with hyalinized walls S100 and SOX10 are diffusely …

2020年11月5日 · Loss of H3K27me3 expression has good sensitivity and robust specificity for the diagnosis of MPNST; however, H3K27me3 expression is retained in epithelioid MPNST (Am J …

Soft tissue stains: AE1 / AE3 ALK1 BCOR beta catenin caldesmon CAMTA1 CCNB3 (pending) CD31 CD34 CD99 CDK4 D2-40 DDIT3 (pending) desmin DOG1 DUX4 EBER EMA ERG …

2024年4月4日 · H3K27me3. The H3K27 trimethylation status distinguishes PFA from PFB. PFA has loss of the H3K27 trimethylation and therefore loss of nuclear staining on H3K27me3 …

2021年12月13日 · 90% are sporadic, with no established risk factors other than smoking in a subset of cases that harbor mutation signatures typical of smoking and mismatch repair …

2023年9月29日 · Loss of H3K27me3; Negative for muscle markers Desmin expression seen in rhabdomyoblastic elements in malignant Triton tumor PEComa (Am J Surg Pathol …

2022年7月27日 · Glioblastoma, IDH wild type is an aggressive, infiltrating, astrocytic glioma that lacks mutations in IDH1, IDH2 and histone H3 genes and is histologically defined by brisk …